The occurrence of a novel coronavirus known as severe acute respiratory syndrome-
coronavirus-2 (SARS-CoV-2), created a serious challenge worldwide. SARS-CoV-2 has …

The lungs are the main site that is affected in severe COVID-19, and post-mortem lung tissue
provides crucial insights into the pathophysiology of severe disease. From basic histology to …

An important component of severe COVID-19 disease is virus-induced endothelilitis. This
leads to disruption of normal endothelial function, initiating a state of failing normal clotting …

Abstract Coronavirus disease 19 (Covid-19) has been declared as a pandemic disease
since March 2020; causing wide array of signs and symptoms, many of which result in …

Abstract Coronavirus disease 2019 (COVID-19) is a pandemic syndrome caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. SARS-CoV-2 infection …

In patients with moderate-to-severe COVID-19 pneumonia, an aberrant post-viral alveolitis
with excessive inflammatory responses and immunothrombosis underpins use of …

We have established considerable expertise in studying the role of platelets in cancer
biology. From this expertise, we were keen to recognize the numerous venous-, arterial …

One of the major pathomechanisms of COVID-19 is the interplay of hyperinflammation and
disruptions in coagulation processes, involving thrombocytes. Antiplatelet therapy (AP) by …

Background COVID-19 patients carry an increased rate of thrombosis. It is controversial to
which extent thrombi in the pulmonary arterial tree really contribute to disease severity with …

(1) Background: Italy accounts for more than 150,000 deaths due to the COVID-19
pandemic, leading the top rank in SARS-CoV-2-caused deceases in Europe. A survey on …