In human cells, the integrity of genetic information is constantly challenged by endogenous
and exogenous chemical agents that can induce DNA damage. To counteract the …

The chemistry of DNA and its repair selectivity control the influence of genomic oxidative
stress on the development of serious disorders such as cancer and heart diseases. DNA is …

Voltammetric DNA sensor has been proposed on the platform of glassy carbon electrode
covered with carbon black with adsorbed pillar [5] arene molecules. Electropolymerization of …

Oxidation of DNA by reactive oxygen species (ROS) yields 8-oxo-7, 8-dihydroguanosine (8-
oxodG) as primary oxidation product, which can lead to downstream G to T transversion …

Damage to DNA from the metabolites of drugs and pollutants constitutes a major human
toxicity pathway known as genotoxicity. Metabolites can react with metal ions and NADPH to …

The concept of the exposome is the encompassing of all the environmental exposures, both
exogenous and endogenous, across the life course. Many, if not all, of these exposures can …

Highlights•A discussion of traditional and cutting edge sensor/array chemical toxicity
screening methods.•Electrochemical assays provide benefits over established tox-screening …

Pteris vittata L. commonly called 'Brake Fern'possesses some interesting medicinal
properties but its chemopreventive potential largely remains unexplored. Therefore, this …

DNA and aptasensors are widely used for fast and reliable detection of disease biomarkers,
pharmaceuticals, toxins, metabolites and other species necessary for biomedical …

Electrochemiluminescence (ECL) may be described as a category of chemiluminescence
(CL) in which one or both reactants are generated electrochemically. 1 Accordingly, ECL …