[HTML][HTML] Phytotherapy in diabetes: Review on potential mechanistic perspectives

HS El-Abhar, MF Schaalan - World journal of diabetes, 2014 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a widely spread epidemic disease that results from the absence of
insulin, decreased secretion and/or impaired function. Since DM is a multi-factorial disease …

[HTML][HTML] Chemistry, pharmacology and therapeutic potential of swertiamarin–A promising natural lead for new drug discovery and development

NSM Fadzil, M Sekar, SH Gan, SR Bonam… - Drug design …, 2021 - ncbi.nlm.nih.gov
Swertiamarin, a seco-iridoid glycoside, is mainly found in Enicostemma littorale Blume (E.
littorale) and exhibits therapeutic activities for various diseases. The present study aimed to …

Antidiabetic Effects of Yam (Dioscorea batatas) and Its Active Constituent, Allantoin, in a Rat Model of Streptozotocin-Induced Diabetes

HK Go, MM Rahman, GB Kim, CS Na, CH Song… - Nutrients, 2015 - mdpi.com
The objective of this study was to investigate the therapeutic efficacies of crude yam
(Dioscorea batatas) powder (PY), water extract of yam (EY), and allantoin (the active …

Protective effect of platycodin D on liver injury in alloxan-induced diabetic mice via regulation of Treg/Th17 balance

T Chen, J Gao, P Xiang, Y Chen, J Ji, P Xie… - International …, 2015 - Elsevier
Platycodin D is a major pharmacological constituent of Platycodi Radix with
immunomodulatory activity. The present study was designed to investigate how platycodin D …

Ameliorating effects of goby fish protein hydrolysates on high-fat-high-fructose diet-induced hyperglycemia, oxidative stress and deterioration of kidney function in rats

R Nasri, O Abdelhedi, I Jemil, I Daoued… - Chemico-Biological …, 2015 - Elsevier
This study investigated the therapeutic potential of undigested goby fish (Zosterisessor
ophiocephalus) muscle proteins (UGP) and their hydrolysates on high-fat-high-fructose diet …

The protective effect of betulinic acid (BA) diabetic nephropathy on streptozotocin (STZ)-induced diabetic rats

R Xie, H Zhang, X Wang, X Yang, S Wu, H Wang… - Food & function, 2017 - pubs.rsc.org
The present study was designed to investigate the protective effect of betulinic acid (BA) on
streptozotocin (STZ)-induced diabetic rats. The rats were intraperitoneally injected with STZ …

Sweroside alleviated LPS-induced inflammation via SIRT1 mediating NF-κB and FOXO1 signaling pathways in RAW264. 7 cells

R Wang, Z Dong, X Lan, Z Liao, M Chen - Molecules, 2019 - mdpi.com
Pterocephalus hookeri was used as a traditional Chinese medicine for the treatment of
rheumatoid arthritis. Sweroside was a main iridoid isolated from P. hookeri. The present …

Chemistry, pharmacology and therapeutic potential of swertiamarin–A promising natural lead for new drug discovery and development

NS Muhamad Fadzil, M Sekar, SH Gan… - Drug Design …, 2021 - Taylor & Francis
Swertiamarin, a seco-iridoid glycoside, is mainly found in Enicostemma littorale Blume (E.
littorale) and exhibits therapeutic activities for various diseases. The present study aimed to …

Anti-Diabetic and Anti-Nephritic Activities of Grifola frondosa Mycelium Polysaccharides in Diet-Streptozotocin-Induced Diabetic Rats Via Modulation on Oxidative …

L Kou, M Du, P Liu, B Zhang, Y Zhang, P Yang… - Applied biochemistry …, 2019 - Springer
Grifola frondosa is an edible fungus with a variety of potential pharmacological activities.
This study investigates the hypoglycemic, anti-diabetic nephritic, and antioxidant properties …

Promising antidiabetic drugs, medicinal plants and herbs: An update

MI Yatoo, A Saxena, A Gopalakris… - International Journal of …, 2017 - elibrary.ru
Diabetes is a chronic endocrine disease with global prevalence and rising incidence.
Diabetes represents a major health issue in all age groups in the present times owing to its …