Macro‐and microvascular endothelial dysfunction in diabetes: 糖尿病诱导的内皮细胞功能损伤

Y Shi, PM Vanhoutte - Journal of diabetes, 2017 - Wiley Online Library
血管内皮细胞和内皮细胞释放的活性因子是调控血管舒张功能的重要因素. 糖尿病是慢性心血管
疾病的高危因素之一. 目前认为高糖和糖尿病引起的内皮细胞功能障碍是造成血管功能改变 …

[HTML][HTML] Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention

LM Butler, Y Perone, J Dehairs, LE Lupien… - Advanced drug delivery …, 2020 - Elsevier
With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

Highlighting diabetes mellitus: the epidemic continues

AM Schmidt - Arteriosclerosis, thrombosis, and vascular biology, 2018 - Am Heart Assoc
Prompted by the observation that atherosclerotic plaques from human diabetic subjects
displayed lower amounts of NADPH (nicotinamide adenine dinucleotide phosphate) …

Cardiomyocyte senescence and cellular communications within myocardial microenvironments

X Tang, PH Li, HZ Chen - Frontiers in Endocrinology, 2020 - frontiersin.org
Cardiovascular diseases have become the leading cause of human death. Aging is an
independent risk factor for cardiovascular diseases. Cardiac aging is associated with …

Endothelial cell–cardiomyocyte crosstalk in heart development and disease

A Colliva, L Braga, M Giacca… - The Journal of …, 2020 - Wiley Online Library
The crosstalk between endothelial cells and cardiomyocytes has emerged as a requisite for
normal cardiac development, but also a key pathogenic player during the onset and …

Role of lipoprotein lipase in lipid metabolism

G Olivecrona - Current opinion in lipidology, 2016 - journals.lww.com
Role of lipoprotein lipase in lipid metabolism : Current Opinion in Lipidology Role of lipoprotein
lipase in lipid metabolism : Current Opinion in Lipidology Log in or Register Subscribe to …

Exosomal CircHIPK3 released from hypoxia‐induced cardiomyocytes regulates cardiac angiogenesis after myocardial infarction

Y Wang, R Zhao, C Shen, W Liu, J Yuan… - Oxidative medicine …, 2020 - Wiley Online Library
Exosomes play critical roles in mediating cell‐to‐cell communication by delivering
noncoding RNAs (including miRNAs, lncRNAs, and circRNAs). Our previous study found …

Endothelial cell–cardiomyocyte crosstalk in diabetic cardiomyopathy

A Wan, B Rodrigues - Cardiovascular research, 2016 - academic.oup.com
The incidence of diabetes is increasing globally, with cardiovascular disease accounting for
a substantial number of diabetes-related deaths. Although atherosclerotic vascular disease …

Lipoprotein lipase: Biosynthesis, regulatory factors, and its role in atherosclerosis and other diseases

PP He, T Jiang, XP OuYang, YQ Liang, JQ Zou… - Clinica chimica acta, 2018 - Elsevier
Lipoprotein lipase (LPL) is a rate-limiting enzyme that catalyzes hydrolysis of the triglyceride
(TG) core of circulating TG-rich lipoproteins including chylomicrons (CM), low-density …

Single-cell transcriptomics reveals endothelial plasticity during diabetic atherogenesis

G Zhao, H Lu, Y Liu, Y Zhao, T Zhu… - Frontiers in cell and …, 2021 - frontiersin.org
Atherosclerosis is the leading cause of cardiovascular diseases, which is also the primary
cause of mortality among diabetic patients. Endothelial cell (EC) dysfunction is a critical …