Recent progress on polysaccharide-based hydrogels for controlled delivery of therapeutic biomolecules

MI Rial-Hermida, A Rey-Rico… - ACS Biomaterials …, 2021 - ACS Publications
A plethora of applications using polysaccharides have been developed in recent years due
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …

Thermoresponsive polysaccharides and their thermoreversible physical hydrogel networks

S Graham, PF Marina, A Blencowe - Carbohydrate polymers, 2019 - Elsevier
Thermoresponsive polymers have been used extensively for various applications including
food additives, pharmaceutical formulations, therapeutic delivery, cosmetics and …

Polysaccharide and polypeptide based injectable thermo-sensitive hydrogels for local biomedical applications

HF Darge, AT Andrgie, HC Tsai, JY Lai - International journal of biological …, 2019 - Elsevier
Injectable thermo-responsive hydrogels have been studied for various biomedical
applications including; drug delivery, cell encapsulation, and tissue repairing. There are …

In situ formation of injectable chitosan-gelatin hydrogels through double crosslinking for sustained intraocular drug delivery

Y Song, N Nagai, S Saijo, H Kaji, M Nishizawa… - Materials Science and …, 2018 - Elsevier
Rapid clearance and low ocular bioavailability are drawbacks of conventional ophthalmic
eye drops. To increase the ocular drug resistance time and improve efficacy, an in situ …

Chitosan: A promising therapeutic agent and effective drug delivery system in managing diabetes mellitus

S Sarkar, D Das, P Dutta, J Kalita, SB Wann… - Carbohydrate …, 2020 - Elsevier
Chitosan, a promising carbohydrate biopolymer is gaining scientific attention in a wide
range of biomedical applications due to its outstanding chemical and pharmacokinetic …

Glucose-Responsive Chitosan Nanoparticle/Poly(vinyl alcohol) Hydrogels for Sustained Insulin Release In Vivo

A Ali, S Saroj, S Saha, SK Gupta… - ACS Applied Materials …, 2023 - ACS Publications
Stimuli-responsive hydrogels (HGs) with a controlled drug release profile are the current
challenge for advanced therapeutic applications. Specifically, antidiabetic drug-loaded …

Thermosensitive Chitosan‐β‐Glycerophosphate Hydrogels as Targeted Drug Delivery Systems: An Overview on Preparation and Their Applications

P Rahmanian-Devin… - Advances in …, 2021 - Wiley Online Library
Today, with the advances in technology and science, more advanced drug delivery
formulations are required. One of these new systems is an intelligent hydrogel. These …

Encapsulation of Triphasia trifolia extracts by pH and thermal dual-sensitive chitosan hydrogels for controlled release

NHN Do, TNA Huynh, TX Le, AC Ha, PK Le - Carbohydrate Polymers, 2023 - Elsevier
Recent studies have developed varied delivery systems incorporating natural compounds to
improve the limitations of plant extracts for clinical use while enabling their controlled …

Chitosan for biomedical applications, promising antidiabetic drug delivery system, and new diabetes mellitus treatment based on stem cell

SI Othman, AM Alturki, GM Abu-Taweel… - International Journal of …, 2021 - Elsevier
Since chitosan's excellent pharmacokinetic and chemical properties, it is an attractive and
promising carbohydrate biopolymer in biomedical applications. Chitosan's beneficial …

Hydrogels as potential drug-delivery systems: Network design and applications

H Shoukat, K Buksh, S Noreen, F Pervaiz… - Therapeutic …, 2021 - Taylor & Francis
Hydrogels are 3D crosslinked polymer matrices having a colossal tendency to imbibe water
and exhibit swelling under physiological conditions without deformation in their hydrophilic …