Distinct populations of stretch‐sensitive mechanoreceptors attached to myelinated vagal
afferents are found in the heart and adjoining coronary and pulmonary circulations …

New Findings What is the topic of the review? Sympathoexcitation and sympathetic control
of blood pressure at high altitude. What advances does it highlight? Sustained …

Millions of people worldwide live at high altitude, being chronically exposed to hypobaric
hypoxia. Hypertension is a major cardiovascular risk factor but data on its prevalence and …

High-altitude (> 2,500 m) exposure results in increased muscle sympathetic nervous activity
(MSNA) in acclimatizing lowlanders. However, little is known about how altitude affects …

Sympathoexcitation is a hallmark of hypoxic exposure, occurring acutely, as well as
persisting in acclimatised lowland populations and with generational exposure in highland …

Key points Humans suffering from polycythaemia undergo multiple circulatory adaptations
including changes in blood rheology and structural and functional vascular adaptations to …

New Findings What is the central question of this study? What is the effect of sub‐maximal
aerobic exercise training on signs and symptoms of chronic mountain sickness (CMS) in …

Background High-altitude populations exhibit distinct cellular, respiratory, and
cardiovascular phenotypes, some of which provide adaptive advantages to hypoxic …

Purpose Following an acute exposure to hypoxia, sympathetic nerve activity remains
elevated. However, this elevated sympathetic nerve activity does not elicit a parallel …

Objective This study aimed to assess biventricular function and mechanics in patients with
the chronic high-altitude disease (CHAD) using cardiovascular MRI and explore the …