pH-Responsive Micellar Nanoparticles for the Delivery of a Self-Amplifying ROS-Activatable Prodrug

VK Kannaujiya, Y Qiao, RH Sheikh, J Xue… - …, 2024 - ACS Publications
The objective of this study is to enhance the therapeutic efficacy of the anticancer drug,
camptothecin (CPT) via a nanoparticle (NP) formulation using a novel amphiphilic …

A robust optimization approach for the breast cancer targeted design of PEtOx-b-PLA polymersomes

UC Oz, ZB Bolat, UU Ozkose, S Gulyuz… - Materials Science and …, 2021 - Elsevier
The equipping of nanoparticles with the peptide moiety recognizing a particular receptor,
enables cell or tissue-specific targeting, therefore the optimization of the targeted …

[HTML][HTML] End-functionalized diblock copolymers by mix and match of poly (2-oxazoline) and polyester building blocks

LM Stafast, N Engel, H Görls, C Weber… - European Polymer …, 2023 - Elsevier
Abstract 2-(4-(Iodomethyl) benzyl) isoindoline-1, 3-dione was utilized as a protected amine-
functionalized initiator for the cationic ring opening-polymerization (CROP) of 2-ethyl-2 …

Combining CROP and ATRP to synthesize pH-responsive poly (2-ethyl-2-oxazoline-b-4-vinylpyridine) block copolymers

RNL de Menezes, MI Felisberti - Polymer Chemistry, 2021 - pubs.rsc.org
Herein, we present the synthesis and characterization of block copolymers based on poly (2-
ethyl-2-oxazoline), a biocompatible and stealth polymer that has drawn considerable …

Poly (2-ethyl-2-oxazoline-co-ethyleneimine)-block-poly (ε-caprolactone) based micelles: synthesis, characterization, peptide conjugation and cytotoxic activity

S Gulyuz, UU Ozkose, MP Khalily, MS Kesici… - New Journal of …, 2021 - pubs.rsc.org
Here we present self-assembled polymeric micelles as potential delivery systems for
therapeutic agents with highly tunable properties. The major goal of this study is to design …