Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

Biological systems display a rich phenomenology of states that resemble the physical states
of matter-solid, liquid and gas. These phases result from the interactions between the …

Control of the structure and function of three-dimensional multicellular tissues depends
critically on the spatial and temporal coordination of cellular physical properties, yet the …

Beyond their many well-established biological aberrations, solid tumours create an
abnormal physical microenvironment that fuels cancer progression and confers treatment …

Living tissues are active, multifunctional materials capable of generating, sensing,
withstanding and responding to mechanical stress. These capabilities enable tissues to …

Injectable hydrogels in regeneration medicine can potentially mimic hierarchical natural
living tissue and fill complexly shaped defects with minimally invasive implantation …

Stiffness and forces are two fundamental quantities essential to living cells and tissues.
However, it has been a challenge to quantify both 3D traction forces and stiffness (or …

Force exertion is an integral part of cellular behavior. Traction force microscopy (TFM) has
been instrumental for studying such forces, providing spatial force measurements at …

Communities of epithelial cells communicate through intercellular interactions, allowing
them to coordinate their motility, which plays a key role in homeostasis, morphogenesis and …

The mechanical properties of cancer cells and their microenvironment contribute to breast
cancer progression. While mechanosensing has been extensively studied using 2D …