[HTML][HTML] IFNAR2 relevance in the clinical outcome of individuals with severe COVID-19
I Fricke-Galindo, A Martínez-Morales… - Frontiers in …, 2022 - frontiersin.org
Interferons (IFNs) are a group of cytokines with antiviral, antiproliferative, antiangiogenic,
and immunomodulatory activities. Type I IFNs amplify and propagate the antiviral response …
and immunomodulatory activities. Type I IFNs amplify and propagate the antiviral response …
[HTML][HTML] Participation of Single-Nucleotide Variants in IFNAR1 and IFNAR2 in the Immune Response against SARS-CoV-2 Infection: A Systematic Review
MF López-Bielma, R Falfán-Valencia, E Abarca-Rojano… - Pathogens, 2023 - mdpi.com
Host genetic factors significantly influence susceptibility to SARS-CoV-2 infection and
COVID-19 severity. Among these genetic factors are single-nucleotide variants (SNVs) …
COVID-19 severity. Among these genetic factors are single-nucleotide variants (SNVs) …
AD-CovNet: An exploratory analysis using a hybrid deep learning model to handle data imbalance, predict fatality, and risk factors in Alzheimer's patients with COVID …
Alzheimer's disease (AD) is the leading cause of dementia globally, with a growing morbidity
burden that may exceed diagnosis and management capabilities. The situation worsens …
burden that may exceed diagnosis and management capabilities. The situation worsens …
[HTML][HTML] Type I interferon pathway genetic variants in severe COVID-19
AFL Montenegro, MAF Clementino, JNU Yaochite - Virus Research, 2024 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by SARS-
CoV-2. According to the World Health Organization (WHO), there have been over 760 …
CoV-2. According to the World Health Organization (WHO), there have been over 760 …
Evaluation of IFNAR2 and TYK2 transcripts' prognostic role in COVID-19 patients: a retrospective study
A Razavi, M Raei, Y Hatami, GS Chokami… - Frontiers in Cellular …, 2024 - frontiersin.org
Background and objectives This study aimed to investigate the possible prognostic
significance of interferon alpha–beta receptor subunit 2 (IFNAR2) and tyrosine kinase 2 …
significance of interferon alpha–beta receptor subunit 2 (IFNAR2) and tyrosine kinase 2 …
[HTML][HTML] Critically-ill COVID-19 susceptibility gene CCR3 shows natural selection in sub-Saharan Africans
Z Sun, L Pan, A Tian, P Chen - Infection, Genetics and Evolution, 2024 - Elsevier
The prevalence of COVID-19 critical illness varies across ethnicities, with recent studies
suggesting that genetic factors may contribute to this variation. The aim of this study was to …
suggesting that genetic factors may contribute to this variation. The aim of this study was to …
[HTML][HTML] A computational approach for structural and functional analyses of disease-associated mutations in the human CYLD gene
AS Roy, T Feroz, MK Islam, MA Munim, DA Supti… - Genomics and …, 2024 - Springer
Tumor suppressor cylindromatosis protein (CYLD) regulates NF-κB and JNK signaling
pathways by cleaving K63-linked poly-ubiquitin chain from its substrate molecules and thus …
pathways by cleaving K63-linked poly-ubiquitin chain from its substrate molecules and thus …
[HTML][HTML] Global trends in COVID-19 Alzheimer's related research: a bibliometric analysis
C Cao, S Li, G Zhou, C Xu, X Chen, H Qiu, X Li… - Frontiers in …, 2023 - frontiersin.org
Background The COVID-19 pandemic has significantly impacted public health, putting
people with Alzheimer's disease at significant risk. This study used bibliometric analysis …
people with Alzheimer's disease at significant risk. This study used bibliometric analysis …
Identification of High-Risk Single Nucleotide Polymorphisms in the Human CYB5R3 Gene Responsible for Recessive Congenital Methemoglobinemia: A …
E Bouatrous, S Nouira, S Menif, H Ouragini - Molecular Syndromology, 2023 - karger.com
Introduction: NADH-cytochrome b5 reductase deficiency due to pathogenic variants in the
CYB5R3 gene causes recessive congenital methemoglobinemia (RCM) type I or type II. In …
CYB5R3 gene causes recessive congenital methemoglobinemia (RCM) type I or type II. In …
Caracterização clínica e sociodemográfica de pacientes com Covid-19 e avaliação da influência de polimorfismos no gene IFNAR2 na gravidade e no desfecho …
AFL Montenegro - 2023 - repositorio.ufc.br
RESUMO A doença do coronavírus 2019 (COVID-19) é uma doença infecciosa causada
pelo SARS-CoV-2, contabilizando mais de 750 milhões de casos confirmados e mais de 6 …
pelo SARS-CoV-2, contabilizando mais de 750 milhões de casos confirmados e mais de 6 …