Propionate prevents loss of the PDIM virulence lipid in Mycobacterium tuberculosis
CV Mulholland, TJ Wiggins, J Cui, C Vilchèze… - Nature …, 2024 - nature.com
Phthiocerol dimycocerosate (PDIM) is an essential virulence lipid of Mycobacterium
tuberculosis. In vitro culturing rapidly selects for spontaneous PDIM-negative mutants that …
tuberculosis. In vitro culturing rapidly selects for spontaneous PDIM-negative mutants that …
Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits
Host-directed therapies (HDTs) represent an emerging approach for bacterial clearance
during tuberculosis (TB) infection. While most HDTs are designed and implemented for …
during tuberculosis (TB) infection. While most HDTs are designed and implemented for …
The effect of Tyloxapol on the metabolome of Mycobacterium tuberculosis
M Opperman, RD Pietersen, M van Reenen… - Journal of …, 2024 - Elsevier
The use of detergents when culturing Mycobacterium tuberculosis (M. tuberculosis) are
essential to prevent clumping. However, these detergents may influence research outcomes …
essential to prevent clumping. However, these detergents may influence research outcomes …
[HTML][HTML] The PDIM paradox of Mycobacterium tuberculosis: new solutions to a persistent problem
CV Mulholland, TJ Wiggins, J Cui, C Vilcheze… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Phthiocerol dimycocerosate (PDIM) is an essential virulence lipid of Mycobacterium
tuberculosis. In vitro culturing rapidly selects for spontaneous mutations that cause PDIM …
tuberculosis. In vitro culturing rapidly selects for spontaneous mutations that cause PDIM …
Developing novel indoles as antitubercular agents and simulated annealing-based analysis of their binding with MmpL3
R Ray, S Das, SR Birangal, HI Boshoff… - Future Medicinal …, 2024 - Taylor & Francis
Aim This research aimed to develop novel indole-2-carboxamides as potential
antitubercular agents using rational drug design. It also focused on identifying the critical …
antitubercular agents using rational drug design. It also focused on identifying the critical …
[HTML][HTML] Identification of Novel Mutations Associated with Bedaquiline Resistance in Mycobacterium Marinum
L Wang, Y Xu, Z Wang - Zoonoses, 2023 - scienceopen.com
Objective: Because infections caused by nontuberculous mycobacteria (NTM) are rapidly
increasing globally, a need exists for developing novel antibiotics and discovering the …
increasing globally, a need exists for developing novel antibiotics and discovering the …
Enterokokové infekce
K Šupáková - 2024 - dk.upce.cz
Bakalářská práce se zabývá bakteriemi rodu Enterococcus a infekcemi, které způsobují. V
práci je shrnuta historie enterokoků, taxonomie, morfologie, biochemické vlastnosti a faktory …
práci je shrnuta historie enterokoků, taxonomie, morfologie, biochemické vlastnosti a faktory …
Health consequences among COVID-19 convalescent patients 30 months post-infection in China
Y Yin, YM Guo, M Xiao, Q Chen, P Long, X Wang… - Zoonoses, 2024 - scienceopen.com
Objective: The health consequences among COVID-19 convalescent patients 30 months
post-infection were described and the potential risk factors were determined. Methods: In …
post-infection were described and the potential risk factors were determined. Methods: In …