Thyroid hormones (THs) play an obligatory role in many fundamental processes underlying
brain development and maturation. The developing embryo/fetus is dependent on maternal …

Background Iodine is an essential nutrient required for the biosynthesis of thyroid hormones,
which are responsible for regulating growth, development and metabolism. Iodine …

Background: Maternal hypothyroxinemia, due to gestational iodine deficiency, causes
neurological dysfunctions in the progeny. Our aim was to determine the effects of delayed …

Objective: This paper re-evaluates the requirements for iodine during pregnancy, lactation
and the neonatal period, and formulates original proposals for the median concentrations of …

: Iodine of maternal origin is required for brain development of the progeny during fetal and
early postnatal life. Therefore, the iodine requirements of the mother are increased during …

During pregnancy and after delivery, the maternal thyroid gland faces several metabolic,
hemodynamic and immunologic changes. In this article we first summarize the current …

The morphological alterations of cortical lamination observed in mouse models of
developmental hypothyroidism prompted the recognition that these experimental changes …

Iodine deficiency remains the most frequent cause worldwide, after starvation, of
preventable mental retardation in children. It causes maternal hypothyroxinemia, which …

The only known mechanism of toxicity for perchlorate is interference with iodide uptake at
the sodium-iodide symporter (NIS). The NIS translocates iodide across basolateral …

Results: Pregnant women in the Vienna area had a median urinary iodine concentration
(UIC) of 87 μg/l. Only 13.8% of the cohort were in the recommended range of 150–249 μg/l …