Cerebrovascular disease underpins vascular dementia (VaD), but structural and functional
changes to the cerebral vasculature contribute to disease pathology and cognitive decline in …

Ophthalmic biomarkers have long played a critical role in diagnosing and managing ocular
diseases. Oculomics has emerged as a field that utilizes ocular imaging biomarkers to …

The choroid is the main source of blood and nourishment supply to the eye. The dysfunction
of the choroid has been implicated in various retinal and choroidal diseases. The …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
neuronal loss, extracellular amyloid-β (Aβ) plaques, and intracellular neurofibrillary tau …

Alzheimer's disease (AD) is the most familiar type of dementia affecting elderly populations
worldwide. Studies of AD patients and AD transgenic mice have revealed alterations in the …

Background The remarkable increase in prevalence and significant morbidity of
neurodegenerative diseases pose a tremendous burden for the health care system …

In 103 subjects with a high genetic risk of developing Alzheimer's disease (AD), family
history (FH) of AD and ApoE ɛ4 characterization (ApoE ɛ4) were analyzed for changes in …

Background Posterior cortical atrophy (PCA) is a form of dementia that frequently displays
significant visual dysfunction and relatively preserved cognitive and executive functions …

Alzheimer's disease (AD) may manifest retinal changes preceding brain pathology. A
transversal case-control study utilized spectral-domain OCT angiography (SD-OCTA) and …

Background The involvement of retina and its vasculature has been recently described in
Alzheimer's disease (AD). Optical coherence tomography angiography (OCTA) is …