Stearoyl-coenzyme A desaturase 1 (SCD1) is a central regulator of fuel metabolism and may
represent a therapeutic target to control obesity and the progression of related metabolic …

Background: High stearic acid (STA) soybean oil is a trans-free, oxidatively stable, non-LDL-
cholesterol-raising oil that can be used to replace trans fatty acids (TFAs) in solid fat …

Context Saturated fatty acid (SFA) vs polyunsaturated fatty acid (PUFA) may promote
nonalcoholic fatty liver disease by yet unclear mechanisms. Objective To investigate if …

De novo lipogenesis (DNL) is a complex yet highly regulated metabolic pathway, and
transcription factors such as liver X receptor (LXR), sterol regulatory element-binding protein …

Recent studies in humans and animal models have highlighted that modulation of stearoyl-
coenzyme A desaturase 1 activity by dietary intervention or genetic manipulation strongly …

OBJECTIVE—The objective of this study is to quantitate expression of genes possibly
contributing to insulin resistance and fat deposition in the human liver. RESEARCH DESIGN …

The quality of dietary fat in relation to cardiovascular disease forms the basis of the diet-
heart hypothesis. Current recommendations on dietary fat now emphasise quality rather …

Stearoyl‐CoA desaturase 1 (SCD1) is an essential lipogenic enzyme that has been shown
to play an intrinsic role in the development of obesity and related conditions, such as insulin …

Dysfunctional lipid metabolism is a key component in the development of metabolic
syndrome, a very frequent condition characterized by dyslipidemia, insulin resistance …

Maintenance of body temperature is achieved partly by modulating lipolysis by a network of
complex regulatory mechanisms. Lipolysis is an integral part of the glycerolipid/free fatty …