Background Low-intensity transcranial focused ultrasound stimulation (TFUS) holds great
promise as a highly focal technique for transcranial stimulation even for deep brain areas …

Noninvasive, transient, and local image-guided blood-brain barrier disruption (BBBD) has
been demonstrated with focused ultrasound exposure in animal models. Most studies have …

We demonstrated the in vivo feasibility of using focused ultrasound (FUS) to transiently
modulate (through either stimulation or suppression) the function of regional brain tissue in …

Antibody-based anticancer agents are promising chemotherapeutic agents. Among these
agents, Herceptin (trastuzumab), a humanized anti-human epidermal growth factor receptor …

The purpose of this study was to test the hypothesis that burst ultrasound in the presence of
an ultrasound contrast agent can disrupt the blood–brain barrier (BBB) with acoustic …

Perturbations in the integrity of the blood-brain barrier have been reported in both humans
and animals under numerous pathological conditions. Although the blood-brain barrier …

Focused ultrasound offers a method to disrupt the blood-brain barrier (BBB) noninvasively
and reversibly at targeted locations. The purpose of this study was to test the safety of this …

Object The goal of this study was to explore the feasibility of using low-frequency magnetic
resonance (MR) image–guided focused ultrasound as a noninvasive method for the …

Background and Purpose—Cellular response to hypoxia is mainly controlled by hypoxia-
inducible factor 1 (HIF-1). The HIF-1 target gene erythropoietin (EPO) has been described as …

Background and Purpose—We tested whether volatile anesthetics induce neuroprotection
that is maintained for a prolonged time. Methods—Rats were pretreated for 3 hours with 1 …