Bariatric surgery for the treatment of chronic kidney disease in obesity and type 2 diabetes mellitus

NG Docherty, CW le Roux - Nature Reviews Nephrology, 2020 - nature.com
Bariatric surgery is an effective therapy for obesity, hypertension and type 2 diabetes
mellitus that is refractory to maximal medical therapy. Results of long-term cohort studies …

Adipokines as mediators of endothelial function and atherosclerosis

G Ntaios, NK Gatselis, K Makaritsis, GN Dalekos - Atherosclerosis, 2013 - Elsevier
For many decades, adipose tissue was considered as an inactive body compartment that
was only used as an energy store. During the recent years, an increasing amount of data …

Women and men have similar amounts of liver and intra-abdominal fat, despite more subcutaneous fat in women: implications for sex differences in markers of …

J Westerbacka, A Corner, M Tiikkainen, M Tamminen… - Diabetologia, 2004 - Springer
Aims/hypothesis Fat accumulation in the liver has been shown to be closely correlated with
hepatic insulin resistance and features of insulin resistance, also independently of body …

Adiponectin and future coronary heart disease events among men with type 2 diabetes

MB Schulze, I Shai, EB Rimm, T Li, N Rifai, FB Hu - Diabetes, 2005 - Am Diabetes Assoc
Adiponectin, predominantly synthesized in the adipose tissue, seems to have substantial
anti-inflammatory properties and to be a major modulator of insulin resistance and …

Relationship between adiponectin and glycemic control, blood lipids, and inflammatory markers in men with type 2 diabetes

MB Schulze, EB Rimm, I Shai, N Rifai, FB Hu - Diabetes care, 2004 - Am Diabetes Assoc
OBJECTIVE—Adiponectin, synthesized in the adipose tissue, appears to play an important
role in hyperglycemia and dyslipidemia, as well as in inflammatory mechanisms, which lead …

Circulating adiponectin levels are associated with better glycemic control, more favorable lipid profile, and reduced inflammation in women with type 2 diabetes

CS Mantzoros, T Li, JAE Manson… - The Journal of …, 2005 - academic.oup.com
Context: Low adiponectin levels, by regulating insulin resistance and metabolic profile, may
contribute to the markedly increased risk of atherosclerosis in diabetic subjects. Objective …

Prevention and treatment of the metabolic syndrome

SS Daskalopoulou, DP Mikhailidis, M Elisaf - Angiology, 2004 - journals.sagepub.com
The prevalence of the metabolic syndrome is increasing owing to lifestyle changes leading
to obesity. This syndrome is a complex association of several interrelated abnormalities that …

Adiponectin and lipoprotein metabolism

GA Christou, DN Kiortsis - Obesity reviews, 2013 - Wiley Online Library
Adiponectin is secreted by the adipose tissue and it has been shown to be down‐regulated
in states of insulin resistance and in cardiovascular disease. It has also been found to be …

Association of adiponectin and resistin with adipose tissue compartments, insulin resistance and dyslipidaemia

MS Farvid, TWK Ng, DC Chan… - Diabetes, obesity …, 2005 - Wiley Online Library
Aim: In this study, we investigated the association of plasma adiponectin and resistin
concentrations with adipose tissue compartments in 41 free‐living men with a wide range of …

Leptin receptors are expressed in coronary arteries, and hyperleptinemia causes significant coronary endothelial dysfunction

JD Knudson, UD Dincer, C Zhang… - American Journal …, 2005 - journals.physiology.org
Obesity is associated with marked increases in plasma leptin concentration, and
hyperleptinemia is an independent risk factor for coronary artery disease. As a result, the …