Therapeutic Modulation of the Host Defense by Hemoadsorption with CytoSorb®—Basics, Indications and Perspectives—A Scoping Review

T Koehler, E Schwier, J Praxenthaler… - International Journal of …, 2021 - mdpi.com
The “normal” immune response to an insult triggers a highly regulated response determined
by the interaction of various immunocompetent cells with pro-and anti-inflammatory …

Hemoadsorption with CytoSorb shows a decreased observed versus expected 28-day all-cause mortality in ICU patients with septic shock: a propensity-score …

WP Brouwer, S Duran, M Kuijper, C Ince - Critical Care, 2019 - Springer
Background and aims Innovative treatment modalities have not yet shown a clinical benefit
in patients with septic shock. To reduce severe cytokinaemia, CytoSorb as an add-on to …

Rationale of hemoadsorption during extracorporeal membrane oxygenation support

LC Napp, S Ziegeler, D Kindgen-Milles - Blood Purification, 2019 - karger.com
Extracorporeal membrane oxygenation (ECMO) and extracorporeal life support are
increasingly used for treating various forms of shock, lung failure, protected interventions …

CytoSorb hemoperfusion markedly attenuates circulating cytokine concentrations during systemic inflammation in humans in vivo

A Jansen, NJB Waalders, DPT van Lier, M Kox… - Critical Care, 2023 - Springer
Abstract Background The CytoSorb hemoadsorption device has been demonstrated to be
capable of clearing inflammatory cytokines, but has not yet been shown to attenuate plasma …

Continuous renal replacement therapy with the addition of CytoSorb cartridge in critically ill patients with COVID‐19 plus acute kidney injury: a case‐series

A Alharthy, F Faqihi, ZA Memish, A Balhamar… - Artificial …, 2021 - Wiley Online Library
Our aim was to investigate continuous renal replacement therapy (CRRT) with CytoSorb
cartridge for patients with life‐threatening COVID‐19 plus acute kidney injury (AKI), sepsis …

Hemoadsorption with CytoSorb in septic shock reduces catecholamine requirements and in-hospital mortality: a single-center retrospective 'genetic'matched analysis

C Rugg, R Klose, R Hornung, N Innerhofer, M Bachler… - Biomedicines, 2020 - mdpi.com
Septic shock is a major burden to healthcare with mortality rates remaining high. Blood
purification techniques aim to reduce cytokine levels and resultant organ failure. Regarding …

[HTML][HTML] Successful reduction of creatine kinase and myoglobin levels in severe rhabdomyolysis using extracorporeal blood purification (CytoSorb®)

O Dilken, C Ince, B Van der Hoven, S Thijsse… - Blood purification, 2020 - karger.com
Rhabdomyolysis, if severe, can lead to acute kidney injury (AKI). Myoglobin is an iron and
oxygen-binding protein that is freely filtered by the glomerulus. Precipitation of myoglobin in …

Blood purification with a cytokine adsorber for the elimination of myoglobin in critically ill patients with severe rhabdomyolysis

C Scharf, U Liebchen, M Paal, M Irlbeck, M Zoller… - Critical Care, 2021 - Springer
Background Rhabdomyolysis is frequently occurring in critically ill patients, resulting in a
high risk of acute kidney injury (AKI) and potentially permanent kidney damage due to …

Biocompatibility and cytotoxic evaluation of new sorbent cartridges for blood hemoperfusion

D Pomarè Montin, G Ankawi, A Lorenzin, M Neri… - Blood …, 2018 - karger.com
Abstract Background/Aims: The use of adsorption cartridges for hemoperfusion (HP) is
rapidly evolving. For these devices, the potential induced cytotoxicity is an important issue …

Cytokine adsorption in severe acute respiratory failure requiring veno-venous extracorporeal membrane oxygenation

M Rieder, D Duerschmied, T Zahn, C Lang… - ASAIO …, 2021 - journals.lww.com
Veno-venous extracorporeal membrane oxygenation (VV ECMO) is a last resort treatment
option for patients with acute respiratory failure (acute respiratory distress syndrome …