Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

Amylin is a pancreatic β-cell hormone that produces effects in several different organ
systems. Here, we review the literature in rodents and in humans on amylin research since …

With their ever-growing prevalence, obesity and diabetes represent major health threats of
our society. Based on estimations by the World Health Organization, approximately 300 …

This review summarizes the receptor-mediated vascular activities of calcitonin gene-related
peptide (CGRP) and the structurally related peptide adrenomedullin (AM). CGRP is a 37 …

Since the discovery of adrenomedullin in 1993 several hundred papers have been
published regarding the regulation of its secretion and the multiplicity of its actions. It has …

Islet amyloid deposition is a pathogenic feature of type 2 diabetes, and these deposits
contain the unique amyloidogenic peptide islet amyloid polypeptide. Autopsy studies in …

Context Energy balance is critical for survival and health, and control of food intake is an
integral part of this process. This report reviews hormonal signals that influence food intake …

Despite dramatic fluctuations in calorie intake, animals maintain a very stable body weight.
The reason is that energy intake and expenditure are precisely matched. Long-term …

VAN ROSSUM, DU-K. HANISCH AND R. QUIRION. Neuroanatomical localization,
pharmacological characterization and functions of CGRP, related peptides and their …

The role of gastrointestinal hormones in the regulation of appetite is reviewed. The
gastrointestinal tract is the largest endocrine organ in the body. Gut hormones function to …