Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …

This review focuses on the role of the peripheral nervous system in cutaneous biology and
disease. During the last few years, a modern concept of an interactive network between …

Calcitonin-gene-related peptide (CGRP) and adrenomedullin are related peptides with
distinct pharmacological profiles. Here we show that a receptor with seven transmembrane …

This review summarizes the receptor-mediated vascular activities of calcitonin gene-related
peptide (CGRP) and the structurally related peptide adrenomedullin (AM). CGRP is a 37 …

Since the discovery of adrenomedullin in 1993 several hundred papers have been
published regarding the regulation of its secretion and the multiplicity of its actions. It has …

The role of peptides as signalling molecules in the nervous system has been studied for
more than 30 years. Neuropeptides and their G-protein-coupled receptors are widely …

I. Introduction T HE calcitonin (CT) and calcitonin gene-related peptide (CGRP) are derived
from the CT/CGRP gene, which is localized in chromosome 11. Alternative splicing of the …

The interaction between components of the nervous system and multiple target cells in the
cutaneous immune system has been receiving increasing attention. It has been observed …

It is becoming clear that receptors that initiate signal transduction by interacting with G-
proteins do not function as monomers, but often require accessory proteins for function …

Vasoactive neuropeptides including substance P and calcitonin gene-related peptide
(CGRP) are localised in sensory nerves which innervate blood vessels. These are the major …