The maintenance of barrier function at exposed surfaces of the mammalian body is essential
for limiting exposure to environmental stimuli, preventing systemic dissemination of …

Cytokines are indispensable signals of the mucosa-associated immune system for
maintaining normal gut homeostasis. An imbalance of their profile in favour of inflammation …

IL-22 plays an important role in mucosal epithelial cell homeostasis. Using a dextran sodium
sulfate-induced mouse model of acute colitis, we observed an IL-23–dependent up …

Inflammatory bowel disease (IBD) is characterized as chronic inflammation in the
gastrointestinal tract, which includes two main subtypes, Crohn's disease and ulcerative …

Skin wound repair requires complex and highly coordinated interactions between
keratinocytes, fibroblasts, and immune cells to restore the epidermal barrier and tissue …

Inflammatory bowel diseases (IBD) include ulcerative colitis and Crohn's disease. The
immune response in ulcerative colitis is different from the Crohn's disease. Accumulating …

Abstract Expression of interleukin (IL)-22, a member of the IL-10 cytokine family, has recently
been reported in a number of human diseases, including mucosal-associated infections and …

Abstract Background and Aims Loss-of-function variants in protein tyrosine phosphatase
non-receptor type-2 [PTPN2] promote susceptibility to inflammatory bowel diseases [IBD] …

Inflammatory bowel disease (IBD) is a chronic disease that requires chronic treatment
throughout the evolution of the disease, with a complex physiopathology that entails great …

BACKGROUND: Microscopic colitis (MC) is a chronic inflammatory bowel disorder of
unknown aetiology comprising collagenous colitis (CC) and lymphocytic colitis (LC). Data on …