The metabolic syndrome (MetS) is defined as the concurrence of obesity-associated cardiovascular risk factors including abdominal obesity, impaired glucose tolerance …
Traditionally, mitochondria are known as" the powerhouse of the cell," responsible for energy (ATP) generation (by the electron transport chain, oxidative phosphorylation, the …
Cardiolipin (CL) is a mitochondrial phospholipid essential for electron transport chain (ETC) integrity. CL-deficiency in humans is caused by mutations in the tafazzin (Taz) gene and …
X Liu, C Guo, Q Zhang - Cell Stress and Chaperones, 2023 - Elsevier
Mitochondria are dynamic organelles that alter their morphology through fission (fragmentation) and fusion (elongation). These morphological changes correlate highly with …
MV Pinti, QA Hathaway… - American Journal of …, 2017 - journals.physiology.org
Heart failure (HF) is an end point resulting from a number of disease states. The prognosis for HF patients is poor with survival rates precipitously low. Energy metabolism is centrally …
Proteomics have passed through a tremendous development in the recent years by the development of ever more sensitive, fast and precise mass spectrometry methods. The …
AM Figueiredo, AC Cardoso, BLB Pereira, RAC Silva… - PLoS …, 2022 - journals.plos.org
Myocardial infarction has a high mortality rate worldwide. Therefore, clinical intervention in cardiac remodeling after myocardial infarction is essential. Açai pulp is a natural product and …
L Wu, X Guo, SD Hartson, MA Davis… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope β, β‐Carotene‐9′, 10′‐dioxygenase 2 (BCO2) is a carotenoid cleavage enzyme localized to the inner mitochondrial membrane in mammals. This study was aimed to assess …
S Rubattu, M Forte, S Raffa - Oxidative Medicine and Cellular …, 2019 - Wiley Online Library
Increased oxidative stress from both mitochondrial and cytosolic sources contributes to the development and the progression of cardiovascular diseases (CVDs), and it is a target of …