Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Cancer immunotherapy and delivery system: an update

M Yang, OT Olaoba, C Zhang, ET Kimchi… - Pharmaceutics, 2022 - mdpi.com
With an understanding of immunity in the tumor microenvironment, immunotherapy turns out
to be a powerful tool in the clinic to treat many cancers. The strategies applied in cancer …

Development of an Inhalable DNA Tetrahedron MicroRNA Sponge

L Yao, G Zhang, Y Wang, Z Liu, J Liang… - Advanced …, 2024 - Wiley Online Library
In designing aerosolized drugs, the challenge lies in achieving optimal penetration and
retention. Existing delivery systems prioritize larger particles for prolonged intrapulmonary …

Amidation of methyl ester-functionalised poly (2-oxazoline) s as a powerful tool to create dual pH-and temperature-responsive polymers as potential drug delivery …

MN Leiske, R Singha, S Jana, BG De Geest… - Polymer …, 2023 - pubs.rsc.org
In the past two decades, thermoresponsive polymers based on tertiary amine groups have
been studied extensively as a class of dual-responsive polymers. In particular, their …

Star Polymer Nanomedicines─ challenges and future perspectives

H Forgham, J Zhu, R Qiao, TP Davis - ACS Applied Polymer …, 2022 - ACS Publications
Star polymers are structures composed of multiple functional linear arms covalently
connected through a central core. The unique conformation of star polymers, with their …

A comprehensive review of small interfering RNAs (siRNAs): mechanism, therapeutic targets, and delivery strategies for cancer therapy

J Zhang, B Chen, C Gan, H Sun, J Zhang… - International Journal of …, 2023 - Taylor & Francis
Small interfering RNA (siRNA) delivery by nanocarriers has been identified as a promising
strategy in the study and treatment of cancer. Short nucleotide sequences are synthesized …

Poly (2-oxazoline)-derived star-shaped polymers as potential materials for biomedical applications: A review

MN Leiske - European Polymer Journal, 2023 - Elsevier
Abstract Poly (2-oxazoline) s (POx) are a unique class of polymers with an enormous
potential for the preparation of functional materials. Their synthesis via the cationic ring …

Emerging trends in nano-driven immunotherapy for treatment of cancer

G Kandasamy, Y Karuppasamy, UM Krishnan - Vaccines, 2023 - mdpi.com
Despite advancements in the development of anticancer medications and therapies, cancer
still has the greatest fatality rate due to a dismal prognosis. Traditional cancer therapies …

Rapid and Efficient Synthesis of Star Polymers via Arm-First Monomer Emulsified Aqueous Ring-Opening Metathesis Polymerization (ME-ROMP)

W Hou, Y Feng, Y Zhou, X Yin, H Liu, Z Liu… - …, 2024 - ACS Publications
The combination of ring-opening metathesis polymerization (ROMP) and the arm-first
strategy is a widely employed “one-pot two-batch” approach for synthesizing star polymers …

Design strategy and research progress of multifunctional nanoparticles in lung cancer therapy

SH Min, W Lei, CJ Jun, ZS Yan, YX Guang… - Expert opinion on …, 2023 - Taylor & Francis
Introduction Lung cancer is one of the cancer types with the highest mortality rate, exploring
a more effective treatment modality that improves therapeutic efficacy while mitigating side …