Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

Neutrophil elastase (NE) is a major inflammatory protease released by neutrophils and is
present in the airways of patients with cystic fibrosis (CF), chronic obstructive pulmonary …

Background Bronchiectasis is predominantly a neutrophilic inflammatory disease. There are
no established therapies that directly target neutrophilic inflammation because little is …

Rationale: E-cigarettes have become increasingly popular and little is known about their
potential adverse health effects. Objectives: To determine the effects of e-cigarette use on …

Beyond their well-known functions in the acute phases of the immune response, neutrophils
play important roles in the various phases of tumor initiation and progression, through the …

Evidence shows that neutrophils can protect the host against pathogens in multiple ways,
including the formation and release of neutrophil extracellular traps (NETs). NETs are web …

The formation of neutrophil extracellular traps (NETs), known as NETosis, was first observed
as a novel immune response to bacterial infection, but has since been found to occur …

Innate immune cells of the respiratory tract are the first line of defense against pathogenic
and environmental insults. Failure of these cells to perform their immune functions leaves …

Neutrophil extracellular traps (NETs) released by activated neutrophils typically consist of
DNA-histone complexes and granule proteins. NETs were originally identified as a host …

Neutrophil extracellular traps (NETs), which are net-like structures composed of DNA,
histones, and antimicrobial proteins, in particular myeloperoxidase (MPO) and elastase …