Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …
over conventional treatment methods. However, achieving high treatment efficacy and deep …
Tailoring gelation mechanisms for advanced hydrogel applications
V Nele, JP Wojciechowski… - Advanced Functional …, 2020 - Wiley Online Library
Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …
and structural versatility has enabled their use across a wide range of applications, including …
[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery
K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …
The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …
candidates for local drug delivery applications. Besides being useful drug carriers …
Bioreducible exosomes encapsulating glycolysis inhibitors potentiate mitochondria-targeted sonodynamic cancer therapy via cancer-targeted drug release and …
Nanocarrier-assisted sonodynamic therapy (SDT) has shown great potential for the effective
and targeted treatment of deep-seated tumors by overcoming the critical limitations of …
and targeted treatment of deep-seated tumors by overcoming the critical limitations of …
[HTML][HTML] For whom the bubble grows: physical principles of bubble nucleation and dynamics in histotripsy ultrasound therapy
Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …
Ultrasound‐propelled nanocups for drug delivery
JJ Kwan, R Myers, CM Coviello, SM Graham, AR Shah… - small, 2015 - Wiley Online Library
Ultrasound‐induced bubble activity (cavitation) has been recently shown to actively
transport and improve the distribution of therapeutic agents in tumors. However, existing …
transport and improve the distribution of therapeutic agents in tumors. However, existing …
A clinical system for non-invasive blood–brain barrier opening using a neuronavigation-guided single-element focused ultrasound transducer
Focused ultrasound (FUS)-mediated blood-brain barrier (BBB) opening is currently being
investigated in clinical trials. Here, we describe a portable clinical system with a therapeutic …
investigated in clinical trials. Here, we describe a portable clinical system with a therapeutic …
Mitochondria-targeting sonosensitizer-loaded extracellular vesicles for chemo-sonodynamic therapy
Sonodynamic therapy (SDT) has emerged as an effective therapeutic modality as it employs
ultrasound (US) to eradicate deep-seated tumors noninvasively. However, the therapeutic …
ultrasound (US) to eradicate deep-seated tumors noninvasively. However, the therapeutic …
Ultrasound-responsive carriers for therapeutic applications
R Chandan, S Mehta, R Banerjee - ACS Biomaterials Science & …, 2020 - ACS Publications
Ultrasound (US)-responsive carriers have emerged as promising theranostic candidates
because of their ability to enhance US-contrast, promote image-guided drug delivery, cause …
because of their ability to enhance US-contrast, promote image-guided drug delivery, cause …