Intervertebral disc (IVD) degeneration (IDD) is a multifactorial pathological process
associated with low back pain (LBP). The pathogenesis is complicated, and the main …

Intervertebral disc degeneration (IVDD) is a common musculoskeletal degenerative disease
worldwide, of which the main clinical manifestation is low back pain (LBP); approximately …

Background Enhanced angiogenesis can promote diabetic wound healing. Mesenchymal
stem cells (MSCs)-derived exosomes, which are cell-free therapeutics, are promising …

Low back pain is a vital musculoskeletal disease that impairs life quality, leads to disability
and imposes heavy economic burden on the society, while it is greatly attributed to …

Growing clinical evidence suggests a correlation between diabetes and more frequent and
severe intervertebral disc failure, partially attributed to accelerated advanced glycation end …

Intervertebral disc (IVD) herniation is a major cause of chronic low back pain and disability.
The current nucleus pulposus (NP) discectomy effectively relieves pain symptoms, but the …

Lumbar intervertebral disc herniation, as a leading cause of low back pain, productivity loss,
and disability, is a common musculoskeletal disorder that results in significant …

As a controllable biological process, regulated cell death (RCD) extensively participates in
cellular homeostasis, organismal development, and the pathogenesis of diseases. This …

Intervertebral disc degeneration (IVDD) is a major cause of low back pain. Diabetes mellitus
is a chronic inflammatory disease that may cause or aggravate IVDD; however, the …

Intervertebral disc degeneration (IVDD), a widely known contributor to low back pain (LBP),
has been proved to be a global health challenging conundrum. Hesperidin (hesperetin-7-O …