R Villalobos-Labra, M Subiabre, F Toledo… - Molecular aspects of …, 2019 - Elsevier
Diabesity is an abnormal metabolic condition shown by patients with obesity that develop type 2 diabetes mellitus. Patients with diabesity present with insulin resistance, reduced …
C Brombach, W Tong, DA Giussani - Trends in molecular medicine, 2022 - cell.com
The prevalence of maternal obesity is increasing at an alarming rate, and is providing a major challenge for obstetric practice. Adverse effects on maternal and fetal health are …
Pregnancy in humans is a multi-step complex physiological process comprising three discrete events, decidualization, implantation and placentation. Its overall success depends …
The endoplasmic reticulum (ER) plays a multifunctional role in lipid biosynthesis, calcium storage, protein folding, and processing. Thus, maintaining ER homeostasis is essential for …
Cardiovascular disease (CVD) is the biggest killer worldwide, composing a major economic burden for health care systems. Obesity and diabetes are dual epidemics on the rise and …
P Valero, G Fuentes, M Cornejo, S Vega… - Molecular Aspects of …, 2022 - Elsevier
A balanced communication between the mother, placenta and foetus is crucial to reach a successful pregnancy. Several windows of exposure to environmental toxins are present …
Highlights•Role of ER stress and autophagy in the pathogenesis of diabetes.•ER stress and autophagy crucial in diabetic microvascular complications pathogenesis.•Modulation of ER …
L Sobrevia, P Valero, A Grismaldo… - … Et Biophysica Acta (BBA …, 2020 - Elsevier
Gestational diabetes mellitus (GDM) is a disease of pregnancy that is associated with d- glucose intolerance and foeto-placental vascular dysfunction. GMD causes mitochondrial …
E Weiss, A Schrüfer, C Tocantins… - The Journal of …, 2023 - Wiley Online Library
High gestational weight gain (GWG) is a cardiovascular risk factor and may disturb neonatal endothelial function. Long non‐coding RNAs (lncRNAs) regulate gene expression …