As a family of hormones with pleiotropic effects, natriuretic peptide (NP) system includes
atrial NP (ANP), B-type NP (BNP), C-type NP (CNP), dendroaspis NP and urodilatin, with NP …

Traditionally associated with female reproduction, oxytocin (OT) was revisited recently and
was revealed to have several new roles in the cardiovascular system. Functional OT …

Due to globalization and sophisticated western and sedentary lifestyle, metabolic syndrome
has emerged as a serious public health challenge. Obesity is significantly increasing …

Phosphorylation of histone H2AX (γH2AX) is known to be the earliest indicator of DNA
double-strand breaks. Recently, it has been shown that mouse embryonic stem cells …

Chronic itch poses major health care and economic burdens worldwide. In 2013, B‐type
natriuretic peptide (BNP) was identified as an itch‐selective neuropeptide and shown to be …

Brain natriuretic peptide (BNP) contributes to heart formation during embryogenesis. After
birth, despite a high number of studies aimed at understanding by which mechanism (s) …

Background Diverse cardiovascular signaling routes have been considered critical for
Chagas cardiomyopathy caused by the protozoan parasite Trypanosoma cruzi. Along this …

Mesenchymal stem cells (MSC), because of their multipotency and ease of purification and
amplification, are an ideal stem cell source for cell therapies. Bone-marrow-derived stem …

Background It has long been proposed that early embryos and reproductive organs exhibit
similar gene expression profiles. However, whether this similarity is propagated to the …

Embryonic stem (ES) cells are originated from the inner cell mass of a blastocyst stage
embryo. They can proliferate indefinitely, maintain an undifferentiated state (self-renewal) …