Roadmap: proton therapy physics and biology

H Paganetti, C Beltran, S Both, L Dong… - Physics in Medicine …, 2021 - iopscience.iop.org
The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Real-time intrafraction motion monitoring in external beam radiotherapy

J Bertholet, A Knopf, B Eiben… - Physics in medicine …, 2019 - iopscience.iop.org
Radiotherapy (RT) aims to deliver a spatially conformal dose of radiation to tumours while
maximizing the dose sparing to healthy tissues. However, the internal patient anatomy is …

Log file‐based dose reconstruction and accumulation for 4D adaptive pencil beam scanned proton therapy in a clinical treatment planning system: implementation …

A Meijers, A Jakobi, K Stützer… - Medical …, 2019 - Wiley Online Library
Background and purpose Motion‐induced uncertainties hamper the clinical implementation
of pencil beam scanning proton therapy (PBS‐PT). Prospective pretreatment evaluations …

[HTML][HTML] A survey of practice patterns for real-time intrafractional motion-management in particle therapy

Y Zhang, P Trnkova, T Toshito, B Heijmen… - Physics and imaging in …, 2023 - Elsevier
Background and purpose Organ motion compromises accurate particle therapy delivery.
This study reports on the practice patterns for real-time intrafractional motion-management in …

AAPM Task Group Report 290: Respiratory motion management for particle therapy

H Li, L Dong, C Bert, J Chang, S Flampouri… - Medical …, 2022 - Wiley Online Library
Dose uncertainty induced by respiratory motion remains a major concern for treating
thoracic and abdominal lesions using particle beams. This Task Group report reviews the …

Future developments in charged particle therapy: improving beam delivery for efficiency and efficacy

J Yap, A De Franco, S Sheehy - Frontiers in Oncology, 2021 - frontiersin.org
The physical and clinical benefits of charged particle therapy (CPT) are well recognized.
However, the availability of CPT and complete exploitation of dosimetric advantages are still …

A new emittance selection system to maximize beam transmission for low‐energy beams in cyclotron‐based proton therapy facilities with gantry

V Maradia, D Meer, DC Weber, AJ Lomax… - Medical …, 2021 - Wiley Online Library
Purpose In proton therapy, the potential of using high‐dose rates in the cancer treatment is
being explored. High‐dose rates could improve efficiency and throughput in standard …

Large energy acceptance gantry for proton therapy utilizing superconducting technology

KP Nesteruk, C Calzolaio, D Meer… - Physics in Medicine …, 2019 - iopscience.iop.org
When using superconducting (SC) magnets in a gantry for proton therapy, the gantry will
benefit from some reduction in size and a large reduction in weight. In this contribution we …

Shortening delivery times for intensity-modulated proton therapy by reducing the number of proton spots: an experimental verification

S Van De Water, MF Belosi, F Albertini… - Physics in Medicine …, 2020 - iopscience.iop.org
Delivery times of intensity-modulated proton therapy (IMPT) can be shortened by reducing
the number of spots in the treatment plan, but this may affect clinical plan delivery. Here, we …

Exploring beamline momentum acceptance for tracking respiratory variability in lung cancer proton therapy: a simulation study

AC Giovannelli, A Köthe, S Safai, D Meer… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Investigating the aspects of proton beam delivery to track organ motion with pencil
beam scanning therapy. Considering current systems as a reference, specify requirements …