Effect of montelukast and MK-886 on hepatic ischemia-reperfusion injury in rats
G Daglar, T Karaca, YN Yuksek, U Gozalan… - Journal of surgical …, 2009 - Elsevier
BACKGROUND: Hepatic ischemia-reperfusion injury (I/R) may occur in transplantation,
trauma, and elective hepatic resections. Leukotrienes have been shown to play a major role …
trauma, and elective hepatic resections. Leukotrienes have been shown to play a major role …
[HTML][HTML] Effects of Wy14643 on hepatic ischemia reperfusion injury in rats
SQ Xu, YH Li, SH Hu, K Chen… - World Journal of …, 2008 - ncbi.nlm.nih.gov
AIM: To investigate the effects and possible mechanisms of Wy14643 on hepatic ischemia-
reperfusion (I/R) injury in rats. METHODS: Thirty male Sprague-Dawley rats weighing 220 …
reperfusion (I/R) injury in rats. METHODS: Thirty male Sprague-Dawley rats weighing 220 …
The isolated perfused liver response to a 'second hit'of portal endotoxin during severe acute pancreatitis
DJ Mole, MA Taylor, NV McFerran, T Diamond - Pancreatology, 2005 - karger.com
Abstract Background/Aim: During severe acute pancreatitis (AP), the liver may show an
exaggerated response to the inflammatory products of gut injury transported in the portal …
exaggerated response to the inflammatory products of gut injury transported in the portal …
Biliary obstruction reduces hepatic killing and phagocytic clearance of circulating microorganisms in rats
S Hoshino, Z Sun, K Uchikura, K Tsugane… - Journal of …, 2003 - Springer
Septic complications are common in patients with biliary obstruction. This is thought to be
related, in part, to dysfunction of the hepatic reticuloendothelial system (RES). It has been …
related, in part, to dysfunction of the hepatic reticuloendothelial system (RES). It has been …
[HTML][HTML] Hepatocellular apoptosis after hepatectomy in obstructive jaundice in rats
DS Wang, KF Dou, KZ Li, ZQ Gao… - World Journal of …, 2003 - ncbi.nlm.nih.gov
AIM: To investigate the hepatocellular apoptosis after hepatectomy in obstructive jaundice
and biliary decompression rats. METHODS: After bile duct ligation for 7 days, rats were …
and biliary decompression rats. METHODS: After bile duct ligation for 7 days, rats were …
Effects of montelukast on the healing of ischemic colon anastomoses
A Celik, E Ergun, N Koksal, AS Celik, E Altinli… - The American Journal of …, 2013 - Elsevier
Background The aim of this study was to examine whether treatment with montelukast, a
selective leukotriene antagonist, would affect anastomotic healing in a reperfused colon rat …
selective leukotriene antagonist, would affect anastomotic healing in a reperfused colon rat …
[HTML][HTML] 5-脂氧合酶与肝脏疾病
谢正元， 文艺， 张吉翔 - 世界华人消化杂志, 2004 - wjgnet.com
脂氧合酶(5-lipoxygenase, 5-LO) 催化花生四烯酸生成5-羟基廿碳四烯酸(5-HETE), 白三烯(LTs)
等类花生酸类物质, 后者在免疫性疾病, 炎症性疾病, 心脑血管疾病, 肿瘤的发生发展过程中起 …
等类花生酸类物质, 后者在免疫性疾病, 炎症性疾病, 心脑血管疾病, 肿瘤的发生发展过程中起 …
5-脂氧合酶激活蛋白选择性抑制剂MK886 对酒精性肝病小鼠模型的影响
杨淑娟， 郭雅玲， 付珊， 何英利… - Journal of Clinical …, 2019 - search.ebscohost.com
目的旨在探究5 r 脂氧合酶激活蛋白(FLAP) 的选择性抑制剂MK886 对小鼠酒精性肝病(ALD)
的影响. 方法48 只雄性昆明种小鼠随机分为4 组, ALD 组, ALD/MK886 组给予Tipoe r nanji …
的影响. 方法48 只雄性昆明种小鼠随机分为4 组, ALD 组, ALD/MK886 组给予Tipoe r nanji …
Role of the specific inhibitor of 5-lipoxygenase-activating protein MK886 in inhibiting alcoholic liver disease in mice
Y ShuJuan, F Shan, H YingLi, Z YingRen, T Zhen - 临床肝胆病杂志, 2019 - lcgdbzz.org
Objective To investigate the effect of MK886, a specific inhibitor of 5-lipoxygenase-activating
protein (FLAP), on alcoholic liver disease (ALD) in mice. Methods A total of 48 male …
protein (FLAP), on alcoholic liver disease (ALD) in mice. Methods A total of 48 male …