The blood–brain barrier (BBB) limits the delivery of therapeutics to the brain but also
represents the main gate for nutrient entrance. Targeting the natural transport mechanisms …

Simple Summary Monoclonal antibodies are increasingly used for a broad range of
diseases. Rising demand must face with time time-consuming and laborious processes to …

Hormone-binding protein (HBP) is a kind of soluble carrier protein and can selectively and
non-covalently interact with hormone. HBP plays an important role in life growth, but its …

Meiotic recombination caused by meiotic double-strand DNA breaks. In some regions the
frequency of DNA recombination is relatively higher, while in other regions the frequency is …

The randomized or cross-validated split of training and testing sets has been adopted as the
gold standard of machine learning for decades. The establishment of these split protocols …

Peptide quantitative structure–activity relationships (pQSARs) have been widely applied to
the statistical modeling and empirical prediction of peptide activity, property and feature. In …

Purpose: KRAS mutations confer adverse prognosis to colorectal cancer, and no targeted
therapies have shown efficacy in this patient subset. Paracrine, nongenetic events induced …

Polystyrene surface‐binding peptides (PSBPs) are useful as affinity tags to build a highly
effective ELISA system. However, they are also a quite common type of target‐unrelated …

S-nitrosylation is one of the most prominent posttranslational modification among proteins. It
involves the addition of nitrogen oxide group to cysteine thiols forming S-nitrosocysteine …

For cystic fibrosis patients, a lung-targeted gene therapy would significantly alleviate
pulmonary complications associated with morbidity and mortality. However, mucus in the …