Targeted delivery by either systemic or local targeting of therapeutics to the bone is an
attractive treatment for various bone metabolism diseases such as osteoporosis …

Aptamers are RNA/DNA oligonucleotide molecules that specifically bind to a targeted
complementary molecule. As potential recognition elements with promising diagnostic and …

Colorectal cancer (CC) is one of the common causes of cancer-related deaths around the
globe. Identification of a novel biomarker for CC is of paramount importance for early …

Due to the massive use of thiamethoxam (TMX) pesticide and the accumulated potential
hazards exposure, the detection of TMX is of great significance to food and ecological safety …

Gene therapy is a promising novel method of tissue regeneration by stimulating or inhibiting
key signaling pathways. However, their therapeutic applications in vivo are largely limited by …

Alzheimer's disease (AD) as common late-life dementia is pathologically associated with the
irreversible and progressive disorder, misfolding, deposition, and accumulation of the brain …

In this work, we propose a novel disposable flexible and screen-printed electrochemical
aptamer-based sensor (aptasensor) for the rapid detection of chlorpyrifos (CPF). To optimize …

In the last couple of decades, aptamers have been one of the preferred biomolecular
recognition elements in biosensors. The platform of aptasensors (aptamer-based …

Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are important liver
enzymes in clinical settings. Their levels are known to be elevated in individuals with …

Synthetic oligonucleic acids known as aptamers exhibit remarkable selectivity and affinity for
target recognition and binding. Selected via an iterative process known as “selective …