Targeting DNA damage response as a potential therapeutic strategy for head and neck squamous cell carcinoma

H Lei, A He, Y Jiang, M Ruan, N Han - Frontiers in Oncology, 2022 - frontiersin.org
Cells experience both endogenous and exogenous DNA damage daily. To maintain
genome integrity and suppress tumorigenesis, individuals have evolutionarily acquired a …

A PRISMA-compliant meta-analysis on association between X-ray repair cross complementing (XRCC1, XRCC2, and XRCC3) polymorphisms and oral cancer …

HR Mozaffari, M Rostamnia, R Sharifi, M Safaei… - Gene, 2021 - Elsevier
Abstract Background Oral Cancer (OC) is one of the leading causes of death and the
disease mainly occurs over 50 years of age. Herein, a meta-analysis aimed to assess the …

Clinicopathological significance of SNPs in RAD51 and XRCC3 in oral and oropharyngeal carcinomas

EM Santos, HBP Santos, FR de Matos… - Oral …, 2019 - Wiley Online Library
Background This study investigated the influence of single nucleotide polymorphisms (SNP)
in RAD51 and XRCC3 on susceptibility to oral and oropharyngeal squamous cell …

Hsa_circ_0009128 mediates progression of oral squamous cell carcinoma by influencing MMP9

H Zhang, Z Wang, Z Zhang - Oral diseases, 2023 - Wiley Online Library
Objectives The objective of this study was to explore the role and mechanism of an
abnormally expressed circRNA (hsa_circ_0009128) in the progression of oral squamous …

The association between the XRCC1 Arg399Gln polymorphism and the risk of head and neck cancer: an updated meta-analysis including 14586 subjects

S Xia, S Wu, M Wang - Technology in cancer research & …, 2021 - journals.sagepub.com
Background: Accumulated evidence shows that DNA repair gene X-ray repair cross
complementing group 1 (XRCC1) may determine individual susceptibility to head and neck …

Influence of Arg399Gln, Arg280His and Arg194Trp XRCC1 gene polymorphisms of Base Excision Repair pathway on the level of 8-oxo-guanine and risk of head and …

J Kabzinski, M Maczynska, D Kaczmarczyk… - Cancer …, 2021 - content.iospress.com
BACKGROUND: Reduced efficiency of DNA repair systems has long been a suspected
factor in increasing the risk of cancer. OBJECTIVE: In this work we investigate influence of …

Measurement of chromosomal instability and level of DNA damage in peripheral blood mononuclear cells of endometrial cancer patients

A Marković, D Grujičić, M Živković Radojević… - …, 2024 - academic.oup.com
Endometrial cancer is one of the most common invasive gynecologic malignancies in
developed countries. The aim of this study was to evaluate chromosomal instability and level …

Excision repair cross‑complementing group 2 upregulation is a potential predictive biomarker for oral squamous cell carcinoma recurrence

YY Wang, PT Fang, CW Su, YK Chen… - Oncology …, 2021 - spandidos-publications.com
Oral cancer is the fourth most common type of cancer among males in Taiwan, and the
prognosis for patients with advanced‑stage oral squamous cell carcinoma (OSCC) remains …

[HTML][HTML] Analysis of salivary detection of P16INK4A and RASSF1A promoter gene methylation and its association with oral squamous cell carcinoma in a Colombian …

LV González-Pérez, DM Isaza-Guzmán… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
Background Epigenetic factors play a fundamental role in the etiopathogenesis of oral
squamous cell carcinoma (OSCC). This study evaluated if salivary detection of …

A literature review and systematic meta-analysis on XRCC3 Thr241Met polymorphism associating with susceptibility of oral cancer

J Fan, W Liu, M Zhang, C Xing - Oncology Letters, 2019 - spandidos-publications.com
Oral cancer is very common, occurring on head as well as neck region with poor prognosis.
The X-ray repair cross-complementing group 3 (XRCC3) gene contained in DNA repairing …