Cardiac biomarkers of acute coronary syndrome: from history to high-sensitivity cardiac troponin

P Garg, P Morris, AL Fazlanie, S Vijayan… - Internal and emergency …, 2017 - Springer
The role of cardiac troponins as diagnostic biomarkers of myocardial injury in the context of
acute coronary syndrome (ACS) is well established. Since the initial 1st-generation assays …

Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome

AR Chapman, KK Lee, DA McAllister, L Cullen… - Jama, 2017 - jamanetwork.com
Importance High-sensitivity cardiac troponin I testing is widely used to evaluate patients with
suspected acute coronary syndrome. A cardiac troponin concentration of less than 5 ng/L …

Machine learning to predict the likelihood of acute myocardial infarction

MP Than, JW Pickering, Y Sandoval, ASV Shah… - Circulation, 2019 - Am Heart Assoc
Background: Variations in cardiac troponin concentrations by age, sex, and time between
samples in patients with suspected myocardial infarction are not currently accounted for in …

[PDF][PDF] Clinical and diagnostic value of cardiac markers in human biological fluids

AM Chaulin, LS Karslyan, EV Bazyuk, DA Nurbaltaeva… - Kardiologiia, 2019 - lib.ossn.ru
The article is devoted to problems of clinicaldiagnostic value of determination of
cardiospecific troponins in human biological fluids. Improvement of laboratory …

High-sensitivity assays for troponin in patients with cardiac disease

D Westermann, JT Neumann, NA Sörensen… - Nature Reviews …, 2017 - nature.com
Troponin is a widely used biomarker in patients with cardiac disease. The use of troponin is
well established in patients with suspected acute myocardial infarction (AMI), but troponin …

Recommendations for Institutions Transitioning to High-Sensitivity Troponin Testing: JACC Scientific Expert Panel

JL Januzzi, SA Mahler, RH Christenson… - Journal of the American …, 2019 - jacc.org
High-sensitivity cardiac troponin (hs-cTn) I or T methods have been in use in certain regions
for years but are now increasingly globally adopted, including in the United States …

Comparison of the efficacy and safety of early rule-out pathways for acute myocardial infarction

AR Chapman, A Anand, J Boeddinghaus, AV Ferry… - Circulation, 2017 - Am Heart Assoc
Background: High-sensitivity cardiac troponin assays enable myocardial infarction to be
ruled out earlier, but the optimal approach is uncertain. We compared the European Society …

Клинико-диагностическая ценность кардиомаркеров в биологических жидкостях человека

АМ Чаулин, ЛС Карслян, ЕВ Григорьева… - Кардиология, 2019 - lib.ossn.ru
Аннотация Статья посвящена вопросам клинико-диагностической ценности
определения сердечных тропонинов в биологических жидкостях человека …

High-sensitivity troponin and the application of risk stratification thresholds in patients with suspected acute coronary syndrome

A Bularga, KK Lee, S Stewart, AV Ferry, AR Chapman… - Circulation, 2019 - Am Heart Assoc
Background: Guidelines acknowledge the emerging role of high-sensitivity cardiac troponin
(hs-cTnl) for risk stratification and the early rule-out of myocardial infarction, but multiple …

Diagnostic performance of high-sensitivity cardiac troponin T strategies and clinical variables in a multisite US cohort

BR Allen, RH Christenson, SA Cohen, R Nowak… - Circulation, 2021 - Am Heart Assoc
Background: European data support the use of low high-sensitivity troponin (hs-cTn)
measurements or a 0/1-hour (0/1-h) algorithm for myocardial infarction to exclude major …