Defining and quantifying the core microbiome: challenges and prospects

AT Neu, EE Allen, K Roy - Proceedings of the National …, 2021 - National Acad Sciences
The term “core microbiome” has become widely used in microbial ecology over the last
decade. Broadly, the core microbiome refers to any set of microbial taxa, or the genomic and …

Metagenomics-enabled microbial surveillance

KKK Ko, KR Chng, N Nagarajan - Nature Microbiology, 2022 - nature.com
Lessons learnt from the COVID-19 pandemic include increased awareness of the potential
for zoonoses and emerging infectious diseases that can adversely affect human health …

Delivery mode affects stability of early infant gut microbiota

CM Mitchell, C Mazzoni, L Hogstrom, A Bryant… - Cell Reports …, 2020 - cell.com
Mode of delivery strongly influences the early infant gut microbiome. Children born by
cesarean section (C-section) lack Bacteroides species until 6–18 months of age. One …

Understanding respiratory microbiome–immune system interactions in health and disease

SK Di Simone, I Rudloff, CA Nold-Petry… - Science translational …, 2023 - science.org
Interactions between the developing microbiome and maturing immune system in early life
are critical for establishment of a homeostasis beneficial to both host and commensals. The …

Coral holobiont cues prime Endozoicomonas for a symbiotic lifestyle

C Pogoreutz, CA Oakley, N Rädecker… - The ISME …, 2022 - academic.oup.com
Endozoicomonas are prevalent, abundant bacterial associates of marine animals, including
corals. Their role in holobiont health and functioning, however, remains poorly understood …

Comparative analysis of 16S rRNA gene and metagenome sequencing in pediatric gut microbiomes

D Peterson, KS Bonham, S Rowland… - Frontiers in …, 2021 - frontiersin.org
The colonization of the human gut microbiome begins at birth, and over time, these microbial
communities become increasingly complex. Most of what we currently know about the …

The gut microbiome and schizophrenia: the current state of the field and clinical applications

T Szeligowski, AL Yun, BR Lennox… - Frontiers in psychiatry, 2020 - frontiersin.org
Schizophrenia is a debilitating psychiatric disorder, leading to both physical and social
morbidity. Despite its importance, the etiology of schizophrenia remains poorly understood …

RNA-based amplicon sequencing is ineffective in measuring metabolic activity in environmental microbial communities

Y Wang, KN Thompson, Y Yan, MI Short, Y Zhang… - Microbiome, 2023 - Springer
Background Characterization of microbial activity is essential to the understanding of the
basic biology of microbial communities, as the function of a microbiome is defined by its …

Species-resolved sequencing of low-biomass or degraded microbiomes using 2bRAD-M

Z Sun, S Huang, P Zhu, L Tzehau, H Zhao, J Lv… - Genome biology, 2022 - Springer
Microbiome samples with low microbial biomass or severe DNA degradation remain
challenging for amplicon-based or whole-metagenome sequencing approaches. Here, we …

Probiotics ameliorate intestinal pathophysiology in a mouse model of Alzheimer's disease

H Kaur, K Nagamoto-Combs, S Golovko… - Neurobiology of …, 2020 - Elsevier
Evidence suggests that changes in intestinal microbiota may affect the central nervous
system. However, it is unclear whether alteration of intestinal microbiota affects progression …