[HTML][HTML] Management of transfusion-dependent β-thalassemia (TDT): Expert insights and practical overview from the Middle East

A El-Beshlawy, H Dewedar, S Hindawi, S Alkindi… - Blood Reviews, 2024 - Elsevier
Abstract β-Thalassemia is one of the most common monogenetic diseases worldwide, with a
particularly high prevalence in the Middle East region. As such, we have developed long …

Problems and approaches for blood transfusion in the developing countries

DJ Roberts, S Field, M Delaney… - Hematology/Oncology …, 2016 - hemonc.theclinics.com
Problems and Approaches for Blood Transfusion in the Developing Countries - Hematology/Oncology
Clinics Skip to Main Content Advertisement Hematology/Oncology Clinics Log in Register Log …

Recent trends in treatment of thalassemia

A El-Beshlawy, M El-Ghamrawy - Blood Cells, Molecules, and Diseases, 2019 - Elsevier
Thalassemia is a common inherited monogenic disease. It is characterized by chronic
hemolysis, ineffective erythropoiesis (IE) and iron overload. Despite advances in transfusion …

[HTML][HTML] Thalidomide for patients with β-thalassemia: a multicenter experience

K Yang, Y Wu, Y Zhou, B Long, Q Lu… - … journal of hematology …, 2020 - ncbi.nlm.nih.gov
Objective This study focused on the efficacy and safety of thalidomide for patients with β-
thalassemia in a multicenter trial. Methods Patients with non-transfusion-dependent …

Clinical features of β-thalassemia and sickle cell disease

PT McGann, AC Nero, RE Ware - Gene and Cell Therapies for Beta …, 2017 - Springer
Sickle cell disease (SCD) and β-thalassemia are among the most common inherited
diseases, affecting millions of persons globally. It is estimated that 5–7% of the world's …

Hydroxyurea for reducing blood transfusion in non‐transfusion dependent beta thalassaemias

WC Foong, JJ Ho, CK Loh… - Cochrane database of …, 2016 - cochranelibrary.com
Background Non‐transfusion dependent beta thalassaemia is a subset of inherited
haemoglobin disorders characterised by reduced production of the beta globin chain of the …

Clinical trial on the effects of thalidomide on hemoglobin synthesis in patients with moderate thalassemia intermedia

Q Ren, YL Zhou, L Wang, YS Chen, YN Ma, PP Li… - Annals of …, 2018 - Springer
To investigate the efficacy and safety of thalidomide in patients with thalassemia intermedia
(TI). Patients with a confirmed diagnosis of TI who met the trial criteria and signed consent …

ATG vs thiotepa with busulfan and cyclophosphamide in matched-related bone marrow transplantation for thalassemia

L Faulkner, C Uderzo, S Khalid, P Marwah… - Blood …, 2017 - ashpublications.org
Matched-related bone marrow transplantation (BMT) may cure> 80% of low-risk children
with severe thalassemia (ST). Very long-term follow-up studies have shown how the …

Thalidomide has a significant effect in patients with thalassemia intermedia

YS Li, Q Ren, Y Zhou, P Li, W Lin, X Yin - Hematology, 2018 - Taylor & Francis
Objective: To investigate the effect of thalidomide in patients with thalassemia intermedia.
Methods: We observed the effect of thalidomide in seven patients with thalassemia …

The use of hydroxyurea in the real life of MIOT network: an observational study

P Ricchi, A Meloni, P Rigano, L Pistoia… - Expert opinion on …, 2022 - Taylor & Francis
Background Hydroxyurea (HU) has been widely used in clinical practice to manage patients
with non-transfusion dependent thalassemia (NTDT). Few data are available about the …