Targeting c-Met in the treatment of urologic neoplasms: Current status and challenges

P Su, M Zhang, X Kang - Frontiers in Oncology, 2023 - frontiersin.org
At present, studies have found that c-Met is mainly involved in epithelial-mesenchymal
transition (EMT) of tumor tissues in urologic neoplasms. Hepatocyte growth factor (HGF) …

Ropivacaine synergizes with sorafenib to induce apoptosis of hepatocellular carcinoma cells via the IL‐6/STAT3 pathway

W Wang, H Lin, D Liu, T Wang, Z Zhu, P Yu… - Cancer …, 2024 - Wiley Online Library
The development of resistance in hepatocellular carcinoma (HCC) cells limits the
effectiveness of sorafenib, but combination therapy with other drugs may have a positive …

KRT80 in hepatocellular carcinoma plays oncogenic role via epithelial–mesenchymal transition and PI3K/AKT pathway

R Hua, X Yan, J He, N Wu, W Yu, P Yu, L Qin - IUBMB life, 2025 - Wiley Online Library
Hepatocellular carcinoma (HCC), a globally prevalent form of cancer, is featured by
aggressive growth and early metastasis. Elucidating the underlying mechanism and …

抗VEGF 及其受体分子靶向药物治疗肝癌机制的研究进展

蓝雪灵, 黄燕妮, 朱敏敏, 马平… - 中国临床药理学与治疗 …, 2024 - manu41.magtech.com.cn
肝细胞癌(hepatocellular carcinoma, HCC) 的发生发展过程与肿瘤血管的形成密切相关.
由血管内皮生长因子(VEGF) 介导的血管生成是肿瘤产生免疫逃逸反应的主要驱动因素, VEGF …

The role of autophagy related 12 (ATG12) in the progression of hepatocellular carcinoma and its prognostic value

H Wang, C Huang, H Cai, Q Ling - Discover Oncology, 2024 - Springer
The aim of our research was to explore the character of autophagy related 12 (ATG12) in the
development of hepatocellular carcinoma (HCC). A total of 145 HCC tissues as well as …

[HTML][HTML] Development and nomogram prediction of early postoperative recurrence in hepatocellular carcinoma based on preoperative CT imaging radiomic features …

Z Xu, W Yuan, Y Zhou, T Yue - Journal of Gastrointestinal …, 2024 - pmc.ncbi.nlm.nih.gov
Background Hepatocellular carcinoma (HCC) is characterized by high postoperative
recurrence rates, and predicting early recurrence is crucial for improving clinical outcomes …

Advances of VEGF signalling pathway in hepatocellular carcinomar invasion and metastasis and therapy

X LAN, Y HUANG, M ZHU, P MA… - Chinese Journal of …, 2024 - manu41.magtech.com.cn
The development of hepatocellular carcinoma (HCC) is closely related to the formation of
tumour blood vessels. VEGF-mediated angiogenesis is a major driver of the immune escape …

Prognostic signature of transmembrane protein family gene for Hepatocellular carcinoma patients based on transcriptomics

K Liu, Y Lv, C Tang, W Yao, B Yang, B Chen - 2022 - researchsquare.com
Transmembrane protein (TMEM) genes family are presented in the biological membrane.
The TMEM gene family is involved in the proliferation, invasion, and migration of …