Dipolar aprotic and ethereal solvents comprise just over 40% of all organic solvents utilized
in synthetic organic, medicinal, and process chemistry. Unfortunately, many of the common …

Transition metal complexes bearing N-heterocyclic carbene ligands (NHCs) have gained a
place of crucial importance in numerous areas of research such as medicinal chemistry …

With the aim of overcoming the well-known limitations of platinum-based antineoplastic
drugs, recent efforts have focused on the development of new anticancer agents containing …

N-heterocyclic carbene (NHC) ligands have evolved from being simple lab curiosities to
tertiary phosphine mimics to finally take center stage as unique supporting ligands in …

Ground-state destabilization of the N–C (O) linkage represents a powerful tool to
functionalize the historically inert amide bond. This burgeoning reaction manifold relies on …

The use of weak bases and mild conditions is currently the most sustainable and attractive
synthetic approach for the preparation of late‐transition metal complexes, some of which are …

N-Acylglutarimides and arylsiloxanes reacted in the presence of Pd (OAc) 2/PCy3, Et3N·
3HF, and LiOAc to provide the corresponding arylketones in good yields. Aryl-, vinyl-, and …

Xanthines, such as caffeine and theophylline, are abundant natural products that are often
present in foods. Leveraging renewable and benign resources for ligand design in …

A straightforward alkali‐metal‐mediated hydroamination of styrenes using biorenewable 2‐
methyltetrahydrofuran as a solvent is reported. Refuting the conventional wisdom of the …

Abstract Robust NHC-palladacycles (NHC= N-heterocyclic carbene) were synthesized and
exhibited high catalytic activity towards Suzuki− Miyaura cross-coupling reactions between …