The HIV treatment landscape for adults has progressed dramatically in recent decades;
however, paediatric populations continue to experience delayed and limited access to …

Emerging clinical studies should prioritize pregnant/lactating people and infants to ensure
such therapies are well tolerated and efficacious. Alongside therapeutic innovation …

Long-acting antiretroviral products have the potential to transform human immunodeficiency
virus (HIV) prevention and treatment approaches in pediatric populations. Broadly …

Background We evaluated dolutegravir pharmacokinetics in infants with human
immunodeficiency virus (HIV) receiving dolutegravir twice daily (BID) with rifampicin-based …

Background WHO guidelines recommend abacavir in first-line antiretroviral treatment for
children and neonates. However, there is no approved dose< 3 months of age, and data in …

Dose recommendations for lamivudine or emtricitabine in children with HIV and chronic
kidney disease (CKD) are absent or not supported by clinical data. Physiologically based …

The perinatal transmission of HIV is preventable through a regimen that includes testing of
all pregnant individuals, antiretroviral treatment (ART) for the pregnant individual …

As of Dec 13, 2023, there have been approximately 772 million confirmed COVID-19 cases
globally and it is estimated that 1% of cases, or 7 million, have resulted in COVID-19-related …

The global strategy to# EndAIDS is underpinned by a call to end all inequities and to ensure
no-one is left behind; but inequities continue, and people are still being left behind. Despite …

Introduction The large number of deaths among children with HIV is driven by poor
antiretroviral treatment (ART) coverage among this cohort. The aim of the study was to …