Subdomain IB is the third major drug binding region of human serum albumin: toward the three-sites model

F Zsila - Molecular pharmaceutics, 2013 - ACS Publications
According to the conventional view, noncovalent association of small molecules with human
serum albumin (HSA) occurs principally at the so-called Sudlow's sites located in …

Dilleniaceae family: an overview of its ethnomedicinal uses, biological and phytochemical profile

CC Lima, RPL Lemos, LM Conserva - Journal of Pharmacognosy …, 2014 - phytojournal.com
The family Dilleniaceae consists of 10-14 genera and about 500 species distributed into four
subfamilies. It is taxonomically isolated and it is the sole representative of Dilleniales. Some …

Study on the interaction between active components from traditional Chinese medicine and plasma proteins

Q Jiao, R Wang, Y Jiang, B Liu - Chemistry Central Journal, 2018 - Springer
Traditional Chinese medicine (TCM), as a unique form of natural medicine, has been used
in Chinese traditional therapeutic systems over two thousand years. Active components in …

Molecular dynamics simulation and binding studies of β-sitosterol with human serum albumin and its biological relevance

B Sudhamalla, M Gokara, N Ahalawat… - The Journal of …, 2010 - ACS Publications
β-Sitosterol is a naturally occurring phytosterol that is widely used to cure atherosclerosis,
diabetes, cancer, and inflammation and is also an antioxidant. Here, we studied the …

MegaStokes BODIPY-triazoles as environmentally sensitive turn-on fluorescent dyes

JC Er, MK Tang, CG Chia, H Liew, M Vendrell… - Chemical …, 2013 - pubs.rsc.org
A novel class of triazole-derivatized BODIPY compounds have been synthesized on solid-
phase by employing mild reaction conditions based on the copper-catalyzed azide–alkyne …

Binding and molecular dynamics studies of 7-hydroxycoumarin derivatives with human serum albumin and its pharmacological importance

DP Yeggoni, M Gokara, D Mark Manidhar… - Molecular …, 2014 - ACS Publications
Human serum albumin (HSA) is one of the most widely studied proteins and is an important
plasma protein responsible for binding and transport of many exogenous and endogenous …

Interaction studies of coumaroyltyramine with human serum albumin and its biological importance

S Neelam, M Gokara, B Sudhamalla… - The Journal of …, 2010 - ACS Publications
N-trans-p-Coumaroyltyramine (CT) isolated from Physalis minima is a phenolic substance
exhibiting many pharmacological activities like potent inhibition of acetyl cholinesterase, cell …

Cytotoxicity and comparative binding mechanism of piperine with human serum albumin and α-1-acid glycoprotein

DP Yeggoni, A Rachamallu, M Kallubai… - Journal of …, 2015 - Taylor & Francis
Human serum albumin (HSA) and α-1-acid glycoprotein (AGP)(acute phase protein) are the
plasma proteins in blood system which transports many drugs. To understand the …

Molecular interaction studies of trimethoxy flavone with human serum albumin

M Gokara, B Sudhamalla, DG Amooru… - PloS one, 2010 - journals.plos.org
Background Human serum albumin (HSA) is the most abundant protein in blood plasma,
having high affinity binding sites for several endogenous and exogenous compounds …

Interaction of oxovanadium (IV)–salphen complexes with bovine serum albumin and their cytotoxicity against cancer

VG Sankareswari, D Vinod, A Mahalakshmi… - Dalton …, 2014 - pubs.rsc.org
Vanadyl compounds of clinical significance are recommended as drugs against diseases
such as tuberculosis, diabetes, cancer, etc. In order to check the potential of the salphen …