Selecting the appropriate formulation and solubility-enabling technology for poorly water
soluble drugs is an essential element in the development of formulations for paediatric …

The drug nanosuspensions is a universal formulation approach for improved drug delivery
of hydrophobic drugs and one the most promising approaches for increasing the …

There has been a tremendous revolution in the field of nanotechnology, resulting in the
advent of novel drug delivery systems known as nanomedicines for diagnosis and therapy …

The alarming numbers of poorly soluble discovery compounds have centered the efforts
towards finding strategies to improve the solubility. One of the attractive approaches to …

Scopoletin is an active coumarin possessing a variety of pharmacological activities,
including anti-hyperuricemic effect, but with poor solubility. To improve its oral bioavailability …

Sorafenib, a potent anticancer drug, has low absorption in the gastrointestinal tract due to its
poor aqueous solubility. The main purpose of this investigation was to design sorafenib …

The purpose of this work was to evaluate the impact of polymer (s) on the dissolution rate,
supersaturation and precipitation of indomethacin amorphous solid dispersions (ASD), and …

Objective: The aim of the present investigation was to investigate the efficacy of solid lipid
nanoparticles (SLNs) to enhance the absorption and bioavailability of lurasidone …

Increasing numbers of poorly water soluble drugs in development has intensified need for
bio-enabling formulations including Lipid-Based Formulations (LBF) and Solid Dispersions …

Abstract Development of nanosuspensions offers a promising tool for formulations involving
poorly water-soluble drugs. In this study, methotrexate (MTX) nanosuspensions were …