Electrochemical immunosensors developed for amyloid-beta and tau proteins, leading biomarkers of Alzheimer's disease

A Sharma, L Angnes, N Sattarahmady, M Negahdary… - Biosensors, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurological disease and a serious cause of
dementia, which constitutes a threat to human health. The clinical evidence has found that …

Chitosan-incorporated bioceramic-based nanomaterials for localized release of therapeutics and bone regeneration: An overview of recent advances and progresses

S Safarzadeh, MR Mozafari… - Current Organic …, 2024 - benthamdirect.com
The usage of nanoparticles in tissue engineering applications has increased significantly in
the last several years. Functional tissues are developed by regulating cell proliferation …

[PDF][PDF] Different Biological Activities and Structure Activity Studies of Acridine and Acridone Derivatives: An Updated Review

S Nandi, S Bhunia, I Debnath, S Hazra… - World J. Pharm …, 2024 - researchgate.net
Acridine and its derivatives' diverse biological functions are thoroughly and up-to-date
analyzed in this review, focusing on the structure-activity relationship (SAR) between them …

Exploring the therapeutic potential of acridines: Synthesis, structure, and biological applications

DSC Marques, L da Silva Lima, JFOM Miranda… - Bioorganic …, 2024 - Elsevier
The objective of this review was to explore the trends and chemical characteristics of
acridines and their derivatives, analyze their contribution to the scientific literature and …

[HTML][HTML] Therapeutic Options in Alzheimer's Disease: From Classic Acetylcholinesterase Inhibitors to Multi-Target Drugs with Pleiotropic Activity

R Cacabelos, O Martínez-Iglesias, N Cacabelos… - Life, 2024 - mdpi.com
Alzheimer's disease (AD) is a complex/multifactorial brain disorder involving hundreds of
defective genes, epigenetic aberrations, cerebrovascular alterations, and environmental risk …

[HTML][HTML] Experiments and Calculation on New N,N-bis-Tetrahydroacridines

MM Hrubaru, C Draghici, FA Ngounoue Kamga… - Molecules, 2024 - mdpi.com
Tetrahydroacridines arouse particular interest due to the potential possibilities of application
in the medical field and protection against corrosion. Bis-tetrahydroacridines were newly …

Selenylated Analogs of Tacrine: Synthesis, In Silico and In Vitro Studies of Toxicology and Antioxidant Properties

M do Sacramento, RB Morais… - Chemistry–An Asian …, 2024 - Wiley Online Library
We present our results on the synthesis and preliminary in silico and in vitro studies of the
toxicology and antioxidant properties of selenylated analogs of Tacrine. Initially, we …

Exploring New Vista for Alzheimer's Disease Drug Targets-Part II

AA Bolinger, J Zhou - Current topics in medicinal chemistry, 2023 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a degenerative neurological condition that progressively impairs
cognitive function, memory retention, and daily functioning. 1 AD is the predominant type of …

[PDF][PDF] The author of the Ph. D. dissertation: Mateusz Olszewski Scientific discipline: Chemistry

EM Bagiński - 2024 - mostwiedzy.pl
Cancer, one of the most devastating diseases known to humanity, continues to present a
significant challenge to societies worldwide. Its impact is profound, affecting individuals …