Fibroblasts are highly dynamic cells that play a central role in tissue repair and fibrosis.
However, the mechanisms by which they contribute to both physiologic and pathologic …

Wound healing requires cooperation between different cell types, among which
macrophages play a central role. In particular, inflammatory macrophages are engaged in …

There are many studies on certain skin cell specifications and their contribution to wound
healing. In this review, we provide an overview of dermal cell heterogeneity and their …

Scars are a serious health concern for burn victims and individuals with skin conditions
associated with wound healing. Here, we identify regenerative factors in neonatal murine …

A wealth of specialized cell populations within the skin facilitates its hair-producing,
protective, sensory, and thermoregulatory functions. How the vast cell-type diversity and …

Much effort has been made to generate human skin organ in the laboratory. Yet, the current
models are limited due to the lack of many critical biological and structural features of the …

Extracellular vesicle (EV)‐based therapies have emerged as a promising means in
regenerative medicine. However, the conventional EV therapy strategy displays some …

Human skin is the largest organ and outermost surface of the human body, and due to the
continuous exposure to various challenges, it is prone to develop injuries, customarily …

Despite the rapid development of therapeutic approaches for skin repair, chronic wounds
such as diabetic foot ulcers remain an unaddressed problem that affects millions of people …

Fibroblasts are the main cell type in the dermis. They are responsible for the synthesis and
deposition of structural proteins such as collagen and elastin, which are integrated into the …