Purpose Colorectal signet-ring cell carcinoma (SRCC) is rare, and very little detailed
information on the molecular biology of the disease is available. Methods The literature on …

Abstract Background and Aim: Recently, the clinical and biological differences between right‐
and left‐sided colon cancers have been widely debated. However, close analyses of these …

Colorectal primary signet ring cell carcinoma (PSRCCR) is a rare entity with a dismal
prognosis, mainly because of delayed diagnosis. The objective of this study was to …

Medullary carcinomas of the pancreas are a recently described, histologically distinct subset
of poorly differentiated adenocarcinomas that may have a unique pathogenesis and clinical …

Most large bowel cancers are moderately to well-differentiated adenocarcinomas comprised
chiefly or entirely of glands lined by tall columnar cells. We have identified a subset of poorly …

Signet ring cell carcinoma and mucinous carcinoma are distinct subtypes of colorectal
adenocarcinoma. The morphologic and molecular spectra of colorectal carcinomas with …

KRAS mutation occurs in 30% to 50% of colorectal cancers (CRCs) and has been
suggested to be associated with proliferation and decreased apoptosis. In this study, we …

Colorectal poorly differentiated adenocarcinoma (ADC) is known to have a poor prognosis
as compared with well to moderately differentiated ADC. The frequency of poorly …

Previous studies have reported that poorly differentiated adenocarcinoma and mucinous
carcinoma of the colon and rectum (Por & Muc) show a low incidence and poor prognosis …

Background Signet ring cell carcinoma (SRCC) is a rare subtype of colorectal cancer (CRC).
The aim of this study was to characterise the genomic alterations and outcomes of SRCC …