Yeast metabolic engineering for carbon dioxide fixation and its application

SR Kim, SJ Kim, SK Kim, SO Seo, S Park, J Shin… - Bioresource …, 2022 - Elsevier
As numerous industrial bioprocesses rely on yeast fermentation, developing CO 2-fixing
yeast strains can be an attractive option toward sustainable industrial processes and carbon …

[HTML][HTML] Microbial L-malic acid production: history, current progress, and perspectives

Y Xi, F Fan, X Zhang - Green Carbon, 2023 - Elsevier
ABSTRACT L-malic acid (L-MA) is an important intermediate in the tricarboxylic acid cycle
and a crucial bulk chemical with various applications in the food, pharmaceutical, and …

Metabolic engineering of the acid-tolerant yeast Pichia kudriavzevii for efficient L-malic acid production at low pH

Y Xi, H Xu, T Zhan, Y Qin, F Fan, X Zhang - Metabolic Engineering, 2023 - Elsevier
Currently, the biological production of L-malic acid (L-MA) is mainly based on the
fermentation of filamentous fungi at near-neutral pH, but this process requires large amounts …

Engineering the metabolism and morphology of the filamentous fungus Trichoderma reesei for efficient L-malic acid production

Y Chen, J Wang, M Wang, A Han, X Zhao… - Bioresource …, 2023 - Elsevier
L-malic acid (MA) is a vital platform chemical with huge market demand because of its broad
industrial applications. A cell factory for MA production was engineered by strengthening the …

Rewiring yeast metabolism for producing 2, 3-butanediol and two downstream applications: Techno-economic analysis and life cycle assessment of methyl ethyl …

JW Lee, SS Bhagwat, N Kuanyshev, YB Cho… - Chemical Engineering …, 2023 - Elsevier
Rising concerns for sustainability and global climate change have driven the development of
sustainable production pathways for biofuels and chemicals from lignocellulosic biomass via …

Metabolic Engineering of Saccharomyces cerevisiae for Vitamin B5 Production

J Guo, X Sun, Y Yuan, Q Chen, Z Ou… - Journal of Agricultural …, 2023 - ACS Publications
Vitamin B5, also called d-pantothenic acid, is an essential vitamin in the human body and is
widely used in pharmaceuticals, nutritional supplements, food, and cosmetics. However, few …

Biological Control Efficacy and Action Mechanism of Klebsiella pneumoniae JCK-2201 Producing Meso-2,3-Butanediol Against Tomato Bacterial Wilt

B Kim, AR Park, CW Song, H Song, JC Kim - Frontiers in Microbiology, 2022 - frontiersin.org
Bacterial wilt caused by Ralstonia solanacearum is a fatal disease that affects the production
of tomatoes and many other crops worldwide. As an effective strategy to manage bacterial …

Cas9-Based Metabolic Engineering of Issatchenkia orientalis for Enhanced Utilization of Cellulosic Hydrolysates

YG Lee, C Kim, N Kuanyshev, NK Kang… - Journal of Agricultural …, 2022 - ACS Publications
Issatchenkia orientalis, exhibiting high tolerance against harsh environmental conditions, is
a promising metabolic engineering host for producing fuels and chemicals from cellulosic …

Integrated fermentative production and downstream processing of L-malic acid by Aspergillus wentii using cassava peel waste

D Gopaliya, S Zaidi, N Srivastava, B Rani… - Bioresource …, 2023 - Elsevier
Abstract L-malic acid (L-MA) is an industrially significant chemical with enormous potential.
The fungal cell factories could be exploited to harvest it on large scales. In our study …

Unveiling malic acid biorefinery: Comprehensive insights into feedstocks, microbial strains, and metabolic pathways

B Xu, W Zhang, E Zhao, J Hong, X Chen, Z Wei… - Bioresource …, 2024 - Elsevier
The over-reliance on fossil fuels and resultant environmental issues necessitate sustainable
alternatives. Microbial fermentation of biomass for malic acid production offers a viable, eco …