[HTML][HTML] Tumor hypoxia and radiotherapy: A major driver of resistance even for novel radiotherapy modalities
C Beckers, M Pruschy, I Vetrugno - Seminars in Cancer Biology, 2024 - Elsevier
Hypoxia in solid tumors is an important predictor of poor clinical outcome to radiotherapy.
Both physicochemical and biological processes contribute to a reduced sensitivity of hypoxic …
Both physicochemical and biological processes contribute to a reduced sensitivity of hypoxic …
Importance of hemoglobin concentration and its modification for the outcome of head and neck cancer patients treated with radiotherapy
CM Hoff - Acta Oncologica, 2012 - Taylor & Francis
Introduction. Hypoxia induced radioresistance has been acknowledged for decades. One of
the indirect evidences of the influence of hypoxia on radiation response comes from the …
the indirect evidences of the influence of hypoxia on radiation response comes from the …
Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck
M Nordsmark, M Overgaard, J Overgaard - Radiotherapy and oncology, 1996 - Elsevier
Background and purpose: Hypoxic tumor cells are known to be relatively radioresistant. The
aim of the study was to correlate oxygenation status and radiation response in advanced …
aim of the study was to correlate oxygenation status and radiation response in advanced …
Tobacco smoking during radiation therapy for head-and-neck cancer is associated with unfavorable outcome
AM Chen, LM Chen, A Vaughan, R Sreeraman… - International Journal of …, 2011 - Elsevier
PURPOSE: To evaluate the effect of continued cigarette smoking among patients
undergoing radiation therapy for head-and-neck cancer by comparing the clinical outcomes …
undergoing radiation therapy for head-and-neck cancer by comparing the clinical outcomes …
Effects of hypoxia on human cancer cell line chemosensitivity
S Strese, M Fryknäs, R Larsson, J Gullbo - BMC cancer, 2013 - Springer
Background Environment inside even a small tumor is characterized by total (anoxia) or
partial oxygen deprivation,(hypoxia). It has been shown that radiotherapy and some …
partial oxygen deprivation,(hypoxia). It has been shown that radiotherapy and some …
Effect of smoking on oxygen delivery and outcome in patients treated with radiotherapy for head and neck squamous cell carcinoma–a prospective study
CM Hoff, C Grau, J Overgaard - Radiotherapy and oncology, 2012 - Elsevier
BACKGROUND: Head and neck cancer patients with high hemoglobin respond better to
irradiation compared to patients with low hemoglobin possibly due to hypoxia induced …
irradiation compared to patients with low hemoglobin possibly due to hypoxia induced …
The importance of haemoglobin level and effect of transfusion in HNSCC patients treated with radiotherapy–results from the randomized DAHANCA 5 study
CM Hoff, HS Hansen, M Overgaard, C Grau… - Radiotherapy and …, 2011 - Elsevier
BACKGROUND AND PURPOSE: Patients with head and neck squamous cell carcinoma
(HNSCC) and a low level of haemoglobin (Hb) often have a poor response to radiation …
(HNSCC) and a low level of haemoglobin (Hb) often have a poor response to radiation …
Impact of smoking status on clinical outcome in oral cavity cancer patients
D Kawakita, S Hosono, H Ito, I Oze, M Watanabe… - Oral oncology, 2012 - Elsevier
The association between smoking status and survival in oral cavity squamous cell
carcinoma (OSCC) patients remains unclear. Therefore, we evaluated the association …
carcinoma (OSCC) patients remains unclear. Therefore, we evaluated the association …
Reduction of carboxyhaemoglobin levels in the venous blood of cigarette smokers following the administration of carbogen
G Macdonald, N Kondor, V Yousefi, A Green… - Radiotherapy and …, 2004 - Elsevier
Cigarette smokers have high carboxyhaemoglobin levels which can promote tumour
radioresistance. Inhalation of carbogen gas shortens the half-life of carboxyhaemoglobin …
radioresistance. Inhalation of carbogen gas shortens the half-life of carboxyhaemoglobin …
Measurement of Tumor Oxygenation: In Vivo Comparison of a Luminescence Fiber-optic Sensor and a Polarographic Electrode in the P22 Tumor
BM Seddon, DJ Honess, B Vojnovic… - Radiation …, 2001 - meridian.allenpress.com
Abstract Seddon, BM, Honess, DJ, Vojnovic, B., Tozer, GM and Workman, P. Measurement
of Tumor Oxygenation: In Vivo Comparison of a Luminescence Fiber-optic Sensor and a …
of Tumor Oxygenation: In Vivo Comparison of a Luminescence Fiber-optic Sensor and a …