[HTML][HTML] Coagulation and cancer: biological and clinical aspects

A Falanga, M Marchetti, A Vignoli - Journal of Thrombosis and Haemostasis, 2013 - Elsevier
Malignancy affects the hemostatic system and the hemostatic system affects malignancy. In
cancer patients there are a number of coagulation abnormalities which provide the …

[HTML][HTML] Preoperative D-dimer level is an independent prognostic factor for non-small cell lung cancer after surgical resection: a systematic review and meta-analysis

HY Deng, X Zheng, R Jiang, RL Wang… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background Whether high preoperative D-dimer level has any impact on long-term survival
of patients with surgically treated non-small cell lung cancer (NSCLC) remains unclear …

Influence of fucoidans on hemostatic system

NE Ustyuzhanina, NA Ushakova, KA Zyuzina, MI Bilan… - Marine drugs, 2013 - mdpi.com
Three structurally different fucoidans from the brown seaweeds Saccharina latissima (SL),
Fucus vesiculosus (FV), and Cladosiphon okamuranus (CO), two chemically modified …

[HTML][HTML] Characterization of the thrombin generation potential of leukemic and solid tumor cells by calibrated automated thrombography

M Marchetti, E Diani, H Ten Cate, A Falanga - haematologica, 2012 - ncbi.nlm.nih.gov
Background Thrombin, the final enzyme of blood coagulation, is a multifunctional serine
protease also involved in the progression of cancer. Tumor cells may activate blood …

[HTML][HTML] Anticoagulation therapy promotes the tumor immune-microenvironment and potentiates the efficacy of immunotherapy by alleviating hypoxia

JU Choi, NK Lee, H Seo, SW Chung… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Purpose Here, this study verifies that cancer-associated thrombosis (CAT) accelerates
hypoxia, which is detrimental to the tumor immune microenvironment by limiting tumor …

Anticoagulation in combination with antiangiogenesis and chemotherapy for cancer patients: evidence and hypothesis

J Wang, C Zhu - OncoTargets and therapy, 2016 - Taylor & Francis
Hypercoagulable state and disorganized angiogenesis are two conspicuous characteristics
during tumor progression. There are a considerable number of clinical trials focusing on the …

A novel risk stratification approach and molecular subgroup characterization based on coagulation related genes in colon adenocarcinoma

X Wu, L Zhu, X Sun, M Xia, S Zhao, B Zhang… - Cancer Cell …, 2024 - Springer
Colon adenocarcinoma (COAD) represents a significant health concern within the
population. Advancing our understanding of COAD is imperative for early detection …

In Vitro Study of Synergic Effect of Cisplatin and Low Molecular Weight Heparin on Oral Squamous Cell Carcinoma

F Camacho-Alonso, T Gómez-Albentosa… - Frontiers in …, 2020 - frontiersin.org
Objectives To evaluate the possible synergic effect of cisplatin and low molecular weight
heparin (LMWH) on oral squamous cell carcinoma (OSCC). Materials and Methods Cisplatin …

Acute promyelocytic leukemia cell adhesion to vascular endothelium is reduced by heparins

A Vignoli, M Marchetti, A Falanga - Annals of Hematology, 2018 - Springer
Adhesion of acute promyelocytic leukemia (APL) cells to endothelial cells (EC) is among the
mechanisms of the APL-associated coagulopathy, responsible for early hemorrhagic deaths …

Enoxaparin versus unfractionated heparin for venous thromboembolism prophylaxis in renally impaired ICU patients

C DeBiase, CA Giuliano, M Doshi… - … : The Journal of …, 2021 - Wiley Online Library
Introduction Intensive care unit (ICU) patients with renal insufficiency are more likely to
develop venous thromboembolism and are at an increased risk for bleeding. There is …