Mutualistic interplay between bacteriophages and bacteria in the human gut

AN Shkoporov, CJ Turkington, C Hill - Nature Reviews Microbiology, 2022 - nature.com
Bacteriophages (phages) are often described as obligate predators of their bacterial hosts,
and phage predation is one of the leading forces controlling the density and distribution of …

Bacteria–phage coevolution as a driver of ecological and evolutionary processes in microbial communities

B Koskella, MA Brockhurst - FEMS microbiology reviews, 2014 - academic.oup.com
Bacteria–phage coevolution, the reciprocal evolution between bacterial hosts and the
phages that infect them, is an important driver of ecological and evolutionary processes in …

Phage cocktail development for bacteriophage therapy: toward improving spectrum of activity breadth and depth

ST Abedon, KM Danis-Wlodarczyk, DJ Wozniak - Pharmaceuticals, 2021 - mdpi.com
Phage therapy is the use of bacterial viruses as antibacterial agents. A primary
consideration for commercial development of phages for phage therapy is the number of …

Phage combination therapies for bacterial wilt disease in tomato

X Wang, Z Wei, K Yang, J Wang, A Jousset, Y Xu… - Nature …, 2019 - nature.com
Bacteriophages have been proposed as an alternative to pesticides to kill bacterial
pathogens of crops. However, the efficacy of phage biocontrol is variable and poorly …

[图书][B] Eco-evolutionary dynamics

AP Hendry - 2017 - degruyter.com
In recent years, scientists have realized that evolution can occur on timescales much shorter
than the" long lapse of ages" emphasized by Darwin—in fact, evolutionary change is …

Understanding the impacts of bacteriophage viruses: from laboratory evolution to natural ecosystems

B Koskella, CA Hernandez… - Annual Review of …, 2022 - annualreviews.org
Viruses of bacteria (bacteriophages or phage) have broad effects on bacterial ecology and
evolution in nature that mediate microbial interactions, shape bacterial diversity, and …

[图书][B] Modeling infectious diseases in humans and animals

MJ Keeling, P Rohani - 2008 - books.google.com
For epidemiologists, evolutionary biologists, and health-care professionals, real-time and
predictive modeling of infectious disease is of growing importance. This book provides a …

Developing phage therapy that overcomes the evolution of bacterial resistance

A Oromí-Bosch, JD Antani… - Annual Review of Virology, 2023 - annualreviews.org
The global rise of antibiotic resistance in bacterial pathogens and the waning efficacy of
antibiotics urge consideration of alternative antimicrobial strategies. Phage therapy is a …

Fitness trade-offs resulting from bacteriophage resistance potentiate synergistic antibacterial strategies

MR Mangalea, BA Duerkop - Infection and immunity, 2020 - Am Soc Microbiol
Bacteria that cause life-threatening infections in humans are becoming increasingly difficult
to treat. In some instances, this is due to intrinsic and acquired antibiotic resistance …

Coevolutionary phage training leads to greater bacterial suppression and delays the evolution of phage resistance

JM Borin, S Avrani, JE Barrick… - Proceedings of the …, 2021 - National Acad Sciences
The evolution of antibiotic-resistant bacteria threatens to become the leading cause of
worldwide mortality. This crisis has renewed interest in the practice of phage therapy. Yet …