There is currently intense interest in the idea that many membraneless organelles might
assemble through phase separation of their constituent molecules into biomolecular' …

The centrosome is the best-understood microtubule-organizing center (MTOC) and is
essential in particular cell types and at specific stages during Drosophila development. The …

Cilia play critical roles during embryonic development and adult homeostasis. Dysfunction of
cilia leads to various human genetic diseases, including many caused by defects in …

Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules,
essential for the formation of motile and sensory cilia. While the structure of the cilium is …

Centrosome positioning is essential for their function. Typically, centrosomes are transported
to various cellular locations through the interaction of centrosomal microtubules (MTs) with …

Drosophila dividing spermatocytes offer a highly suitable cell system in which to investigate
the coordinated reorganization of microtubule and actin cytoskeleton systems during cell …

Reproductive and respiratory organs, along with brain ventricles, are lined by multiciliated
epithelial cells (MCC) that generate cilia-powered fluid flows. MCC hijack the centrosome …

ABSTRACT A centrosome consists of a pair of centrioles and pericentriolar material (PCM).
We manipulated expression of PCNT, a key PCM protein, and investigated roles of PCM in …

The centriole, or basal body, is the center of attachment between the sperm head and tail.
While the distal end of the centriole templates the cilia, the proximal end associates with the …

Cilia and flagella are conserved eukaryotic organelles essential for cellular signaling and
motility. Cilia dysfunctions cause life-threatening ciliopathies, many of which are due to …