Huperzine A (HupA), an alkaloid found in the club moss Huperzia serrata, has been used for centuries in Chinese folk medicine to treat dementia. The effects of this alkaloid have been …
S Meng-Zhen, L Ju, Z Lan-Chun, D Cai-Feng… - Heliyon, 2022 - cell.com
Background Millions of people suffer from Alzheimer's disease (AD) and Parkinson's disease (PD) worldwide. Due to their complex pathology, no effective pharmacological …
S Kumar, D Kumari, B Singh - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The plants are from the genus Rauvolfia Plum. ex L.(Apocynaceae), which is represented by 74 species with many synonyms, and distributed …
R Vrabec, G Blunden, L Cahlíková - International Journal of Molecular …, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia in elderly people; currently, there is no efficient treatment. Considering the increase in life expectancy …
Simple Summary Plant-derived terpenes have been a research interest in the recent years, as they are believed to possess the ability to function as a cholinesterase inhibitor. As the …
Y Wang, T Zheng, Y Huo, W Du - ACS Chemical Neuroscience, 2022 - ACS Publications
Type-2 diabetes mellitus (T2DM) is one of the most concerning public health problems because of its high incidence, multiple complications, and difficult treatment. Human islet …
H Zhang, D Wang, J Sun, Y Wang, S Wu… - International Journal of …, 2022 - mdpi.com
Huperzine A (HupA) is a natural acetylcholinesterase inhibitor (AChEI) with the advantages of high efficiency, selectivity as well as reversibility and can exhibit significant therapeutic …
J Li, Y Wu, S Dong, Y Yu, Y Wu, B Xiang, Q Li - Molecules, 2023 - mdpi.com
Neuronal injury and apoptosis are important causes of the occurrence and development of many neurodegenerative diseases, such as cerebral ischemia, Alzheimer's disease, and …
COVID-19 patients can exhibit a wide range of clinical manifestations affecting various organs and systems. Neurological symptoms have been reported in COVID-19 patients …