[HTML][HTML] Role of gut microbiota in type 2 diabetes pathophysiology

M Gurung, Z Li, H You, R Rodrigues, DB Jump… - …, 2020 - thelancet.com
A substantial body of literature has provided evidence for the role of gut microbiota in
metabolic diseases including type 2 diabetes. However, reports vary regarding the …

Microbial regulation of organismal energy homeostasis

PD Cani, M Van Hul, C Lefort, C Depommier… - Nature …, 2019 - nature.com
The gut microbiome has emerged as a key regulator of host metabolism. Here we review the
various mechanisms through which the gut microbiome influences the energy metabolism of …

Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism

A Zarrinpar, A Chaix, ZZ Xu, MW Chang… - Nature …, 2018 - nature.com
Antibiotic-induced microbiome depletion (AIMD) has been used frequently to study the role
of the gut microbiome in pathological conditions. However, unlike germ-free mice, the effects …

The influence of the gut microbiome on host metabolism through the regulation of gut hormone release

AM Martin, EW Sun, GB Rogers, DJ Keating - Frontiers in physiology, 2019 - frontiersin.org
The microbial community of the gut conveys significant benefits to host physiology. A clear
relationship has now been established between gut bacteria and host metabolism in which …

Rebuilding the gut microbiota ecosystem

A Gagliardi, V Totino, F Cacciotti, V Iebba… - International journal of …, 2018 - mdpi.com
A microbial ecosystem in which bacteria no longer live in a mutualistic association is called
dysbiotic. Gut microbiota dysbiosis is a condition related with the pathogenesis of intestinal …

Impact of antibiotics on the human microbiome and consequences for host health

DV Patangia, C Anthony Ryan, E Dempsey… - …, 2022 - Wiley Online Library
It is well established that the gut microbiota plays an important role in host health and is
perturbed by several factors including antibiotics. Antibiotic‐induced changes in microbial …

Obesity and diabetes—Not only a simple link between two epidemics

A Chobot, K Górowska‐Kowolik… - Diabetes/metabolism …, 2018 - Wiley Online Library
Diabetes (DM) as well as obesity, due to their increasing incidence, were recognized as
epidemic by the World Health Organization. Obesity is involved not only in the …

Gut microbiota and their neuroinflammatory implications in Alzheimer's disease

VV Giau, SY Wu, A Jamerlan, SSA An, SY Kim… - Nutrients, 2018 - mdpi.com
The bidirectional communication between the central nervous system (CNS) and the gut
microbiota plays a pivotal role in human health. Increasing numbers of studies suggest that …

Antibiotics in the pathogenesis of diabetes and inflammatory diseases of the gastrointestinal tract

AC Fenneman, M Weidner, LA Chen… - Nature Reviews …, 2023 - nature.com
Antibiotic use is increasing worldwide. However, the use of antibiotics is clearly associated
with changes in gut microbiome composition and function, and perturbations have been …

Adjunctive Probiotic Lactobacillus rhamnosus Probio-M9 Administration Enhances the Effect of Anti-PD-1 Antitumor Therapy via Restoring Antibiotic-Disrupted Gut …

G Gao, T Ma, T Zhang, H Jin, Y Li, LY Kwok… - Frontiers in …, 2021 - frontiersin.org
Emerging evidence supports that the efficacy of immune checkpoint blockade (ICB) therapy
is associated with the host's gut microbiota, as prior antibiotic intake often leads to poor …