Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

In the last ten years, gabapentin and pregabalin have been becoming dispensed broadly
and sold on black markets, thereby, exposing millions to potential side-effects. Meanwhile …

Importance Substance use disorders are a major source of morbidity and mortality in the
United States. National data comparing the prevalence of substance use disorder diagnoses …

Objectives: Identify the etiology of opioid use disorder medical conditions and emergencies.
Outline the appropriate evaluation of opioid use disorder. Review the management options …

Even though evidence-based treatment for opioid use disorders (OUD) is effective, almost
four in five Americans with OUD do not receive any form of treatment. The gap in access to …

Introduction Opioid use disorder has grown rapidly over the years and is a public health
crisis in the US Although opioid use disorder is widely studied, relatively little is known about …

Background New persistent opioid use occurs in 3% to 14% of patients after elective
surgery, but is poorly described after cardiothoracic surgery. We examined the association of …

Opioid use disorder is highly prevalent and can be fatal. At least 2.1 million Americans 12
years and older had opioid use disorder in 2016, and approximately 47,000 Americans died …

The opioid epidemic is a significant public health crisis that has caused extensive harm and
devastation in the United States. This literature review aimed to identify the contributing …

Background The expansion of the US opioid epidemic has led to significant increases in
infections, such as infective endocarditis (IE), which is tied to injection behaviors. We aimed …